3-AMino-6-chloro-2-Methylisonicotinic acid

Base Information

Chemical Name:3-AMino-6-chloro-2-Methylisonicotinic acid
CAS No.:1073182-66-7
Molecular Formula:C7H7ClN2O2
Molecular Weight:186.59568
Hs Code.:
Mol file:1073182-66-7.mol

Synonyms:3-AMino-6-chloro-2-Methylisonicotinic acid

Suppliers and Price of 3-AMino-6-chloro-2-Methylisonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Amino-6-chloro-2-methylisonicotinicacid 95+%
1g
$ 853.00

Chemenu
3-amino-6-chloro-2-methylisonicotinicacid 95%
1g
$ 805.00

Total 3 raw suppliers

Chemical Property of 3-AMino-6-chloro-2-Methylisonicotinic acid

Chemical Property:

PSA：76.21000
LogP:1.90500

Purity/Quality:

95+% ^*data from raw suppliers

3-Amino-6-chloro-2-methylisonicotinicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-AMino-6-chloro-2-Methylisonicotinic acid

There total 7 articles about 3-AMino-6-chloro-2-Methylisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1073182-63-4
3-amino-6-chloro-2-methylisonicotinic acid methyl ester

: 1073182-66-7
3-amino-6-chloro-2-methylisonicotinic acid

Guidance literature:: 3-amino-6-chloro-2-methylisonicotinic acid methyl ester; With methanol; sodium hydroxide; water; for 2.5h; Heating / reflux;

With hydrogenchloride; water; at 20 ℃;

Reference yield:

: 5350-93-6
6-Chloro-pyridin-3-ylamine

: 1073182-66-7
3-amino-6-chloro-2-methylisonicotinic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: tert-butyl alcohol / 12 h / 50 °C

2.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / diethyl ether; hexane / -78 - -10 °C

2.2: 0.5 h

2.3: pH ~ 3

3.1: potassium hydroxide; water / 5 h / 90 °C

3.2: 20 °C

4.1: methanol; diethyl ether; toluene / 2 h / 20 °C

5.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 27 h / 20 - 80 °C

6.1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 7 h / Heating / reflux

7.1: methanol; sodium hydroxide; water / 2.5 h / Heating / reflux

7.2: 20 °C

With methanol; potassium hydroxide; sodium hydroxide; N-Bromosuccinimide; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; water; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; methanol; diethyl ether; hexane; water; N,N-dimethyl-formamide; toluene; tert-butyl alcohol;

Reference yield:

: 1073182-59-8
methyl 5-amino-2-chloroisonicotinate

: 1073182-66-7
3-amino-6-chloro-2-methylisonicotinic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 27 h / 20 - 80 °C

2.1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 7 h / Heating / reflux

3.1: methanol; sodium hydroxide; water / 2.5 h / Heating / reflux

3.2: 20 °C

With methanol; sodium hydroxide; N-Bromosuccinimide; water; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; N,N-dimethyl-formamide;