LY-2584702 (tosylate salt)

Base Information

• Chemical Name: LY-2584702 (tosylate salt)
• CAS No.: 1082949-68-5
• Molecular Formula: C28H27F4N7O3S
• Molecular Weight: 617.6176928
• Hs Code.: 2933998090
• Mol file: 1082949-68-5.mol

Synonyms:LY-2584702 (tosylate salt);LY2584702 Tosylate;4-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine p-toluenesulfonate;4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1)

Chemical Property of LY-2584702 (tosylate salt)

Chemical Property:

• PSA: 138.27000
• LogP: 6.68280

Purity/Quality:

98% min ^*data from raw suppliers

LY-2584702 Tosylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: LY-2584702 is a p70 S6 kinase inhibitor with anti-tumor activity.

Technology Process of LY-2584702 (tosylate salt)

There total 1 articles about LY-2584702 (tosylate salt) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazol[3,4-d]pyrimidine (1082949-67-4) + toluene-4-sulfonic acid (104-15-4) → 4-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine p-toluenesulfonate (1082949-68-5)

Guidance literature:

In water; acetone; at 20 - 55 ℃; for 2.33h; Product distribution / selectivity;

upstream raw materials:

4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazol[3,4-d]pyrimidine

toluene-4-sulfonic acid

Refernces