Technology Process of benzyl 4-amino-3-oxopiperazine-1-carboxylate
There total 7 articles about benzyl 4-amino-3-oxopiperazine-1-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrazine;
In
methanol;
for 3.5h;
Heating / reflux;
- Guidance literature:
-
4-(benzyloxycarbonyl)-2-piperazinone;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.5h;
With
O-diphenylphosphinyl hydroxylamine;
at 50 ℃;
for 15h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1,4-dioxane / 15 h / Heating / reflux
2: sodium cyanoborohydride; acetic acid / acetonitrile / 5.5 h
3: diphenylether / 2 h / Heating / reflux
4: hydrazine / methanol / 3.5 h / Heating / reflux
With
sodium cyanoborohydride; acetic acid; hydrazine;
In
1,4-dioxane; methanol; diphenylether; acetonitrile;