1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid

Base Information

Chemical Name:1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid
CAS No.:327971-19-7
Molecular Formula:C10H13NO4S2
Molecular Weight:275.34
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60377866
Wikidata:Q82167230
ChEMBL ID:CHEMBL1537909
Mol file:327971-19-7.mol

Synonyms:327971-19-7;1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid;1-(2-thienylsulfonyl)piperidine-4-carboxylic acid;1-thiophen-2-ylsulfonylpiperidine-4-carboxylic acid;1-(thiophen-2-ylsulfonyl)piperidine-4-carboxylic acid;1-(thiophene-2-sulfonyl)piperidine-4-carboxylic acid;IFLab1_003502;Cambridge id 7209955;Oprea1_140672;MLS001229729;SCHEMBL3916331;CHEMBL1537909;DTXSID60377866;UHLPQMBGBPAJFX-UHFFFAOYSA-N;HMS1421P04;HMS2902N11;BBL001439;MFCD01925604;STL102639;AKOS000114724;SDCCGMLS-0065503.P001;SMR000611857;VS-00848;EN300-00373;1-(2-thienylsulfonyl)-4-piperidinecarboxylic acid;AF-399/25039001;SR-01000444084;1-(thien-2-ylsulfonyl)piperidine-4-carboxylic acid;SR-01000444084-1;1-(thiophen-2-ylsulfonyl)piperidine-4-carboxylicacid;Z45524831;F0774-0001;1-(thiophene-2-sulfonyl)-piperidine-4-carboxylic acid, AldrichCPR

Suppliers and Price of 1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid
500mg
$ 200.00

Matrix Scientific
1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid
1g
$ 308.00

Crysdot
1-(Thiophen-2-ylsulfonyl)piperidine-4-carboxylicacid 97%
5g
$ 790.00

American Custom Chemicals Corporation
1-(THIOPHENE-2-SULFONYL)-PIPERIDINE-4-CARBOXYLIC ACID 95.00%
2.5G
$ 1037.94

American Custom Chemicals Corporation
1-(THIOPHENE-2-SULFONYL)-PIPERIDINE-4-CARBOXYLIC ACID 95.00%
1G
$ 750.68

American Custom Chemicals Corporation
1-(THIOPHENE-2-SULFONYL)-PIPERIDINE-4-CARBOXYLIC ACID 95.00%
5G
$ 1252.83

AK Scientific
1-(2-thienylsulfonyl)piperidine-4-carboxylicacid
1g
$ 1200.00

AK Scientific
1-(2-thienylsulfonyl)piperidine-4-carboxylicacid
100mg
$ 537.00

AK Scientific
1-(2-thienylsulfonyl)piperidine-4-carboxylicacid
20mg
$ 267.00

AK Scientific
1-(2-thienylsulfonyl)piperidine-4-carboxylicacid
1mg
$ 117.00

Total 5 raw suppliers

Chemical Property of 1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid

Chemical Property:

Boiling Point:485.7±55.0 °C(Predicted)
PKA:4.34±0.20(Predicted)
PSA：111.30000
Density:1.476±0.06 g/cm3(Predicted)
LogP:2.25210
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:275.02860024
Heavy Atom Count:17
Complexity:382

Purity/Quality:

98%min ^*data from raw suppliers

1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1C(=O)O)S(=O)(=O)C2=CC=CS2

Technology Process of 1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid

There total 2 articles about 1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 498-94-2
isonipecotic acid

: 16629-19-9
thiophene-2-sulfonyl chloride

: 327971-19-7
1-(thiophen-2-ylsulfonyl)piperidine-4-carboxylic acid

Guidance literature:: With sodium hydrogencarbonate; In water; acetone; for 1h;
DOI:10.1021/jm801042a

Reference yield:

: 328032-17-3
1-(thiophene-2-sulfonyl)-piperidine-4-carboxylic acid ethyl ester

: 327971-19-7
1-(thiophen-2-ylsulfonyl)piperidine-4-carboxylic acid

Guidance literature:: 1-(thiophene-2-sulfonyl)-piperidine-4-carboxylic acid ethyl ester; With potassium hydroxide; water; In ethanol; at 20 ℃; for 4.5h;

With hydrogenchloride; In ethanol; water; pH=2;