5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile

Base Information

Chemical Name:5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile
CAS No.:1272354-22-9
Molecular Formula:C26H18N6
Molecular Weight:414.469
Hs Code.:
Mol file:1272354-22-9.mol

Synonyms:5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile

Chemical Property:

PSA：87.38000
LogP:5.31058

Purity/Quality:

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Technology Process of 5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile

There total 2 articles about 5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.2%

: 402718-29-0
3-cyanopyridine-5-boronic acid pinacol ester

: 1272353-93-1
2-chloro-5-phenyl-N-(pyridin-2-ylmethyl)quinazolin-4-amine

: 1272354-22-9
5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.6b01889