N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide

Base Information

Chemical Name:N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide
CAS No.:1272356-40-7
Molecular Formula:C₂₆H₂₁N₇O
Molecular Weight:447.499
Hs Code.:

Synonyms:N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide

Chemical Property:

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Technology Process of N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide

There total 2 articles about N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1272354-22-9
5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile

: 1272356-40-7
N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide

Guidance literature:: With hydroxylamine hydrochloride; potassium carbonate; In ethanol; at 80 ℃; for 16h;

Reference yield:

: 1272356-40-7
C₂₆H₂₁N₇O

Guidance literature:

Reference yield: 23.0%

: 5781-53-3
monomethyl oxalyl chloride

: 1272356-40-7
N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide

: 1272355-14-2
methyl 3-(5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)pyridin-3-yl)-1,2,4-oxadiazole-5-carboxylate

Guidance literature:: monomethyl oxalyl chloride; N-hydroxy-5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinimidamide; In 1,2-dichloro-ethane; at 0 - 20 ℃; for 2h;

With trichlorophosphate; In 1,2-dichloro-ethane; for 1.5h; Reflux;