8-methoxy-3,4-dihydro-2H-1-benzopyran-3-amine

Base Information

Chemical Name:8-methoxy-3,4-dihydro-2H-1-benzopyran-3-amine
CAS No.:112904-73-1
Molecular Formula:C₁₀H₁₃NO₂
Molecular Weight:179.219
Hs Code.:2932999099
European Community (EC) Number:859-564-9
DSSTox Substance ID:DTXSID20552713
Nikkaji Number:J668.373H
Mol file:112904-73-1.mol

Synonyms:112904-73-1;8-methoxychroman-3-amine;8-methoxy-3,4-dihydro-2H-1-benzopyran-3-amine;(8-METHOXY-3,4-DIHYDRO-2H-CHROMEN-3-YL)AMINE;8-methoxy-3,4-dihydro-2H-chromen-3-amine;MFCD08544307;2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY-;8-Methoxy-3-chromanamine;3-amino-8-methoxychroman;3-amino -8-methoxychroman;SCHEMBL7600724;DTXSID20552713;YPFAOXHRMCVHOP-UHFFFAOYSA-N;AMY22728;AKOS004912338;BS-37086;SY083795;CS-0441096;EN300-68565;G54686;Z1095213938

Suppliers and Price of 8-methoxy-3,4-dihydro-2H-1-benzopyran-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Methoxy-3,4-dihydro-2H-1-benzopyran-3-amine
50mg
$ 90.00

SynQuest Laboratories
8-Methoxy-3,4-dihydro-2H-1-benzopyran-3-amine
1 g
$ 728.00

Crysdot
8-Methoxychroman-3-amine 95+%
1g
$ 432.00

Chemenu
8-Methoxychroman-3-amine 95%
1g
$ 408.00

ChemBridge Corporation
(8-methoxy-3,4-dihydro-2H-chromen-3-yl)amine 90%
1 g
$ 235.00

Apolloscientific
8-Methoxy-3,4-dihydro-2H-1-benzopyran-3-amine
1g
$ 615.00

American Custom Chemicals Corporation
2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY- 95.00%
5G
$ 1590.46

American Custom Chemicals Corporation
2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY- 95.00%
2.5G
$ 1255.54

American Custom Chemicals Corporation
2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY- 95.00%
1G
$ 867.10

Alichem
8-Methoxychroman-3-amine
1g
$ 359.04

Total 12 raw suppliers

Chemical Property of 8-methoxy-3,4-dihydro-2H-1-benzopyran-3-amine

Chemical Property:

Melting Point:203-205℃ (ethanol ethyl ether )
Boiling Point:299.3±40.0 °C(Predicted)
PKA:7.91±0.20(Predicted)
PSA：44.48000
Density:1.128±0.06 g/cm3(Predicted)
LogP:2.45970
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

8-Methoxy-3,4-dihydro-2H-1-benzopyran-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC2=C1OCC(C2)N

Technology Process of 8-methoxy-3,4-dihydro-2H-1-benzopyran-3-amine

There total 6 articles about 8-methoxy-3,4-dihydro-2H-1-benzopyran-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 119284-78-5
3-acetamido-8-methoxychroman

: 112904-73-1
8-methoxychroman-3-amine

Guidance literature:: With hydrogenchloride; 1.) methanol, 90 deg C, 6 h; 2.) r.t., 17 h;
DOI:10.1016/0223-5234(88)90203-6

Reference yield:

: 137279-47-1
8-methoxy-3,4-dihydro-3-nitro-2H-1-benzopyran

: 112904-73-1
8-methoxychroman-3-amine

Guidance literature:: With hydrazine hydrate; nickel; In ethanol; at 45 ℃; for 0.5h;
DOI:10.1016/0223-5234(91)90145-D

Reference yield:

: 119284-77-4
3-acetamido-8-methoxy-4-chromanone

: 112904-73-1
8-methoxychroman-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / H₂ / 5percent Pd/C / acetic acid; HClO₄ / 24 h / 30 °C / 2280 Torr

2: 67 percent / 25percent HCl / 1.) methanol, 90 deg C, 6 h; 2.) r.t., 17 h

With hydrogenchloride; hydrogen; palladium on activated charcoal; In perchloric acid; acetic acid;
DOI:10.1016/0223-5234(88)90203-6