N,N-Diphenyl-1H-imidazole-1-carboxamide

Base Information

• Chemical Name: N,N-Diphenyl-1H-imidazole-1-carboxamide
• CAS No.: 2875-79-8
• Molecular Formula: C16H13N3O
• Molecular Weight: 263.299
• Mol file: 2875-79-8.mol

Synonyms:N,N-Diphenyl-1H-imidazole-1-carboxamide;N,N-diphenylimidazole-1-carboxamide

Chemical Property of N,N-Diphenyl-1H-imidazole-1-carboxamide

Chemical Property:

• PSA: 38.13000
• LogP: 3.68950
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99.5% ^*data from raw suppliers

N,N-Diphenyl-1H-imidazole-1-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-Diphenyl-1H-imidazole-1-carboxamide

There total 2 articles about N,N-Diphenyl-1H-imidazole-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

diphenylamine (122-39-4) + 1,1'-carbonyldiimidazole (530-62-1) → N,N-diphenylimidazole-1-carboxamide (2875-79-8)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; for 48h; Inert atmosphere; Reflux;

DOI:10.1039/c2ob25412c

Reference yield:

→ N,N-diphenylimidazole-1-carboxamide (2875-79-8)

Guidance literature:

Diphenylcarbamoylchlorid, Imidazol;

DOI:10.1021/jo00974a020

Reference yield: 90.0%

indole (120-72-9) + N,N-diphenylimidazole-1-carboxamide (2875-79-8) → N,N-diphenyl-1H-indole-3-carboxamide

Guidance literature:

With trimethylaluminum; In toluene; at 110 ℃; for 48h; regioselective reaction; Inert atmosphere;

DOI:10.1002/ejoc.201300085

upstream raw materials:

diphenylamine

1,1'-carbonyldiimidazole

Downstream raw materials:

(R,Z)-4-hydroxy-N,N-diphenylpent-2-ynamide

1,1-dibenzyl-3,3-diphenylurea

diphenylformamide

benzhydrylidene(methyl)amine

Refernces

• 1、 Velavan,Sumathi,Balasubramanian. "Unsymmetrical tetrasubstituted ureas from tertiary carbamoylimidazole: Activation by AlMe3". supporting information; experimental part. p. 6420 - 6431. Retrieved 2012/09/05.