S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole

Base Information

Chemical Name:S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole
CAS No.:345264-15-5
Molecular Formula:C16H18N2O2
Molecular Weight:270.32632
Hs Code.:
Mol file:345264-15-5.mol

Synonyms:S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole;tert-butyl 3,4-dihydro-[1,4]diazepino[6,7,1-hi]indole-2(1H)-carboxylate

Suppliers and Price of S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Boc-1,2,3,4-tetrahydropyrrolo-[3,2,1-jk][1,4]benzodiazepine 95+%
1g
$ 1634.00

Crysdot
2-Boc-1,2,3,4-tetrahydropyrrolo-[3,2,1-jk][1,4]benzodiazepine 95+%
1g
$ 775.00

Total 9 raw suppliers

Chemical Property of S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole

Chemical Property:

PSA：34.47000
LogP:3.32990

Purity/Quality:

97% ^*data from raw suppliers

2-Boc-1,2,3,4-tetrahydropyrrolo-[3,2,1-jk][1,4]benzodiazepine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole

There total 13 articles about S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 748811-03-2
2-[(tert-butoxycarbonyl)(1H-indol-7-ylmethyl)amino]ethyl methanesulfonate

: 345264-15-5
S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;
DOI:10.1016/j.bmcl.2004.05.088

Reference yield:

: 1074-88-0
1H-indole-7-carbaldehyde

: 345264-15-5
S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/c / methanol / 20 °C / 760 Torr

2: aq. K₂CO₃ / tetrahydrofuran / 0 °C

3: Et₃N / tetrahydrofuran / 2 h / 0 °C

4: NaH / dimethylformamide / 0 °C

With hydrogen; sodium hydride; potassium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm049768a