2-CYANOBENZALDEHYDE OXIME

Base Information

• Chemical Name: 2-CYANOBENZALDEHYDE OXIME
• CAS No.: 909772-06-1
• Molecular Formula: C8H6N2O
• Molecular Weight: 146.148
• Mol file: 909772-06-1.mol

Synonyms:2-CYANOBENZALDEHYDE OXIME

Chemical Property of 2-CYANOBENZALDEHYDE OXIME

Chemical Property:

• PSA: 56.38000
• LogP: 1.36638

Purity/Quality:

97% ^*data from raw suppliers

2-CYANOBENZALDEHYDEOXIME 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CYANOBENZALDEHYDE OXIME

There total 1 articles about 2-CYANOBENZALDEHYDE OXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

o-formylbenzonitrile (7468-67-9) → C8H6N2O (909772-06-1)

Guidance literature:

With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; at 30 ℃; for 1h;

DOI:10.1016/j.bmcl.2014.07.031

Reference yield: 37.0%

C8H6N2O (909772-06-1) + C8H9N3 → 2-(5-(6-(dimethylamino)pyrimidin-4-yl)isoxazol-3-yl)benzonitrile

Guidance literature:

With bis-[(trifluoroacetoxy)iodo]benzene; In methanol; water; at 20 ℃;

DOI:10.1021/acscombsci.7b00032

Reference yield:

C8H6N2O (909772-06-1) → phthalonitrile (91-15-6)

Guidance literature:

With fluorosulfonyl fluoride; triethylamine; In acetonitrile; at 20 ℃; for 0.25h; Schlenk technique;

DOI:10.1055/s-0037-1611840

upstream raw materials:

o-formylbenzonitrile

Downstream raw materials:

C₂₀H₁₂N₂O₄

C₈H₅ClN₂O

phthalonitrile

Refernces

• 1、 Chen, Ming,Liu, Jiyuan,Tian, Zhen,Liu, Xueying,Zhang, Shengyong. "Synthesis, cytotoxic activity and binding model analysis of novel isoxazole-docetaxel analogues with C3′-N modification". . p. 1355 - 1365. Retrieved 2018/04/10.
• 2、 Shakeel-u-Rehman,Masood-ur-Rahman,Tripathi, Vijay K.,Singh, Jasvinder,Ara, Tabassum,Koul, Surrinder,Farooq, Saleem,Kaul, Anupurna. "Synthesis and biological evaluation of novel isoxazoles and triazoles linked 6-hydroxycoumarin as potent cytotoxic agents". . p. 4243 - 4246. Retrieved 2014/09/17.