5-AMino-2-Methyl-2-pentanol

Base Information

• Chemical Name: 5-AMino-2-Methyl-2-pentanol
• CAS No.: 108262-66-4
• Molecular Formula: C6H15NO
• Molecular Weight: 117.1894
• Mol file: 108262-66-4.mol

Synonyms:5-AMino-2-Methyl-2-pentanol

Chemical Property of 5-AMino-2-Methyl-2-pentanol

Chemical Property:

• PSA: 46.25000
• LogP: 1.19650
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

5-Amino-2-methyl-2-pentanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-AMino-2-Methyl-2-pentanol

There total 4 articles about 5-AMino-2-Methyl-2-pentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-(4-Hydroxy-4-methylpentyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione (107767-68-0) → 5-amino-2-methylpentan-2-ol (108262-66-4)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; at -78 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja200551y

Reference yield:

5-(dibenzylamino)-2-methylpentan-2-ol (1455037-19-0) → 5-amino-2-methylpentan-2-ol (108262-66-4)

Guidance literature:

With 10 wt% Pd(OH)2 on carbon; hydrogen; In methanol; at 40 ℃; for 3h; under 2585.81 Torr;

Reference yield:

4-methyl pentanamine (5344-20-7) → 5-amino-2-methylpentan-2-ol (108262-66-4)

Guidance literature:

With dipotassium peroxodisulfate; sulfuric acid; In water; at 65 ℃; for 2h; Reagent/catalyst; Solvent; Sealed tube;

DOI:10.1021/acs.orglett.6b03731

upstream raw materials:

1-(4-Hydroxy-4-methylpentyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione

3,7-dimethyl-1-(4-metylpentyl)-1H-purine-2,6-(2H,6H)-dione

5-(dibenzylamino)-2-methylpentan-2-ol

4-methyl pentanamine

Downstream raw materials:

N-(3-hydroxy-4-methylpentyl)benzamide