(4-Methylpiperazin-1-yl)piperidin-4-yl-methanone dihydrochloride

Base Information

• Chemical Name: (4-Methylpiperazin-1-yl)piperidin-4-yl-methanone dihydrochloride
• CAS No.: 1019852-03-9
• Molecular Formula: C₁₁H₂₁N₃O*ClH
• Molecular Weight: 247.768
• Hs Code.: 2933599090
• Mol file: 1019852-03-9.mol

Synonyms:(4-Methyl-piperazin-1-yl)-piperidin-

Chemical Property of (4-Methylpiperazin-1-yl)piperidin-4-yl-methanone dihydrochloride

Chemical Property:

• PSA: 35.58000
• LogP: 1.56860
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1-Methyl-4-[(piperidin-4-yl)carbonyl]piperazine dihydrochloride 98.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-Methylpiperazin-1-yl)piperidin-4-yl-methanone dihydrochloride

There total 1 articles about (4-Methylpiperazin-1-yl)piperidin-4-yl-methanone dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

tert-butyl 4-[(4-methylpiperazin-1-yl)carbonyl]piperidine-1-carboxylate → (4-methylpiperazin-1-yl)(piperidin-4-yl)methanone hydrochloride (1018826-44-2,1019852-03-9)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 1h; Heating / reflux;

Reference yield: 71.0%

(4-methylpiperazin-1-yl)-(4-piperidyl)methanone dihydrochloride (1019852-03-9) → 4-[(4-methyl-1-piperazinyl)methyl]piperidine (735262-46-1)

Guidance literature:

(4-methylpiperazin-1-yl)-(4-piperidyl)methanone dihydrochloride; With lithium aluminium tetrahydride; In tetrahydrofuran; for 48h; Reflux;

With water; In tetrahydrofuran;

With sodium hydroxide; In tetrahydrofuran;

Downstream raw materials:

4-[(4-methyl-1-piperazinyl)methyl]piperidine

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