735262-46-1

Usage

Organic compound

It is an organic compound, meaning it is primarily composed of carbon, hydrogen, and other elements such as nitrogen in this case.

Heterocyclic structure

The compound contains a six-membered ring with two nitrogen atoms and four carbon atoms, making it a heterocyclic compound.

Piperazine class

It belongs to the class of piperazines, which are a group of heterocyclic organic compounds.

Derivative of piperazine

1-Methyl-4-(Piperidin-4-Ylmethyl)Piperazine is a derivative of the piperazine compound, meaning it is structurally similar but has modifications.

Piperidine ring linkage

The compound contains a piperidine ring linked to a piperazine ring, which contributes to its unique properties.

Pharmaceutical research potential

Due to its structural properties, 1-Methyl-4-(Piperidin-4-Ylmethyl)Piperazine has the potential to be used in pharmaceutical research for the development of pharmacologically active compounds.

Synthesis applications

1-Methyl-4-(Piperidin-4-Ylmethyl)Piperazine can be utilized in the synthesis of various pharmacologically active compounds, making it a valuable building block in drug development.

Intermediate in drug production

The compound may have potential applications as an intermediate in the production of pharmaceutical drugs and other organic compounds, further highlighting its importance in the field of chemistry and drug development.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 1019852-03-9 (4-methylpiperazin-1-yl)-(4-piperidyl)methanone dihydrochloride 
• 63214-56-2 (4-methyl-piperazin-1-yl)-piperidin-4-yl-methanone 
• 1013330-08-9 1-((1-benzylpiperidin-4-yl)methyl)-4-methylpiperazine 

Downstream Products

• 1241538-21-5 C₁₃H₂₄N₆S 
• 1241537-79-0 6-(4-isopropylphenyl)-2-{4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl}imidazo[2,1-b][1,3,4]thiadiazole 

Relevant academic research and scientific papers

Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety

We herein report the design and synthesis of benzothiazinones containing a piperidine moiety as new antitubercular agents based on the structure feature of IMB-ZR-1 discovered in our lab. Some of them were found to have good in vitro activity (MIC 1 μg/

A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells

Disruption of the reprogrammed energy management system of malignant cells is a prioritized goal of targeted cancer therapy. Two regulators of this system are the Fer kinase, and its cancer cell specific variant, FerT, both residing in subcellular compartments including the mitochondrial electron transport chain. Here, we show that a newly developed inhibitor of Fer and FerT, E260, selectively evokes metabolic stress in cancer cells by imposing mitochondrial dysfunction and deformation, and onset of energy-consuming autophagy which decreases the cellular ATP level. Notably, Fer was also found to associate with PARP-1 and E260 disrupted this association thereby leading to PARP-1 activation. The cooperative intervention with these metabolic pathways leads to energy crisis and necrotic death in malignant, but not in normal human cells, and to the suppression of tumors growth in vivo. Thus, E260 is a new anti-cancer agent which imposes metabolic stress and cellular death in cancer cells.

6-PHENYL-2-[((PIPERIDIN-4-YLMETHYL)-PIPERAZIN-1YL) OR PIPERAZIN 1-YLMETHYL)-PIPERIDIN-1-YL)]-IMIDAZO[2,1-B][1,3,4]THIADIAZOLE DERIVATIVES AND THEIR USE

The present invention is directed to novel heterocyclic compounds, their synthesis and pharmaceutical compositions comprising them for the treatment of disorders, in particular, cancer.

Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain

The present invention concerns novel benzenesulphonamide compounds, defined by formula I and the description, their method of preparation and their use in therapy.