1-Cyclohexyloctahydropyrrolo[1,2-a]pyrazine

Base Information

• Chemical Name: 1-Cyclohexyloctahydropyrrolo[1,2-a]pyrazine
• CAS No.: 155206-41-0
• Molecular Formula: C₁₃H₂₄N₂
• Molecular Weight: 208.347
• Hs Code.: 2933990090
• Mol file: 155206-41-0.mol

Synonyms:1-Cyclohexyloctahydropyrrolo[1,2-a]pyrazine;1-cyclohexyl-1,2,3,4,6,7,8,8a-octahydropyrrolo[1,2-a]pyrazine

Chemical Property of 1-Cyclohexyloctahydropyrrolo[1,2-a]pyrazine

Chemical Property:

• PSA: 15.27000
• LogP: 2.26960

Purity/Quality:

98%min ^*data from raw suppliers

1-Cyclohexyloctahydropyrrolo[1,2-a]pyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Cyclohexyloctahydropyrrolo[1,2-a]pyrazine

There total 3 articles about 1-Cyclohexyloctahydropyrrolo[1,2-a]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-phenyl-3,4-dihydropyrrolo<1,2-a>pyrazine (111609-55-3) → 1-cyclohexyloctahydropyrrolo<1,2-a>pyrazine (155206-41-0)

Guidance literature:

With hydrogen; nickel; In triethylamine; at 160 - 170 ℃; for 2h; under 111720 Torr;

DOI:10.1007/BF00780552

Reference yield: 63.0%

1-Cyclohexyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine (112758-87-9) → 1-cyclohexyloctahydropyrrolo<1,2-a>pyrazine (155206-41-0)

Guidance literature:

With hydrogen; acetic acid; platinum(IV) oxide; for 24h;

DOI:10.1007/BF00780552

Reference yield: 31.5%

1-Phenyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine (112758-89-1) → 1-cyclohexyloctahydropyrrolo<1,2-a>pyrazine (155206-41-0) + 1-phenyloctahydropyrrolo<1,2-a>pyrazine

Guidance literature:

With hydrogen; acetic acid; platinum(IV) oxide; for 30h; Yield given. Title compound not separated from byproducts;

DOI:10.1007/BF00780552

upstream raw materials:

1-phenyl-3,4-dihydropyrrolo<1,2-a>pyrazine

1-Cyclohexyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine

1-Phenyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine