(S)-tert-butyl 2-((tert-butoxycarbonyl)aMino)-5-nitropentanoate

Base Information

Chemical Name:(S)-tert-butyl 2-((tert-butoxycarbonyl)aMino)-5-nitropentanoate
CAS No.:887610-86-8
Molecular Formula:C₁₄H₂₆N₂O₆
Molecular Weight:318.37
Hs Code.:
Mol file:887610-86-8.mol

Synonyms:(S)-tert-butyl 2-((tert-butoxycarbonyl)aMino)-5-nitropentanoate;Pentanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-5-nitro-, 1,1-dimethylethyl ester

Suppliers and Price of (S)-tert-butyl 2-((tert-butoxycarbonyl)aMino)-5-nitropentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of (S)-tert-butyl 2-((tert-butoxycarbonyl)aMino)-5-nitropentanoate

Chemical Property:

Boiling Point:423.2±40.0 °C(Predicted)
PKA:8.38±0.29(Predicted)
Density:1.102±0.06 g/cm3(Predicted)

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (S)-tert-butyl 2-((tert-butoxycarbonyl)aMino)-5-nitropentanoate

There total 7 articles about (S)-tert-butyl 2-((tert-butoxycarbonyl)aMino)-5-nitropentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 173690-59-0
(tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-5-iodopentanoate)

: 887610-86-8
tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-5-nitropentanoate

Guidance literature:: With sodium nitrite; In N,N-dimethyl-formamide; for 4h;
DOI:10.1021/acs.orglett.7b01498

Reference yield:

: 2480-93-5
Boc-Orn(Z)-OH

: 887610-86-8
tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-5-nitropentanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / K₂CO₃; benzyltriethylammonium chloride / N,N-dimethyl-acetamide / 24 h / 55 - 60 °C

2: hydrogen / 10 percent Pd on charcoal / ethyl acetate / 3 h / ambient pressure

3: 0.73 g / 3-chloroperoxybenzoic acid / 1,2-dichloro-ethane / 0.37 h / Heating

With N-benzyl-N,N,N-triethylammonium chloride; hydrogen; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; 10% palladium on active carbon; In N,N-dimethyl acetamide; ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1002/ejoc.200500856

Reference yield:

: 53054-02-7
N_α-(1,1-dimethylethoxycarbonyl)-N_δ-(phenylmethoxycarbonyl)-L-ornithine 1,1-dimethylethyl ester

: 887610-86-8
tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-5-nitropentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / 10 percent Pd on charcoal / ethyl acetate / 3 h / ambient pressure

2: 0.73 g / 3-chloroperoxybenzoic acid / 1,2-dichloro-ethane / 0.37 h / Heating

With hydrogen; 3-chloro-benzenecarboperoxoic acid; 10% palladium on active carbon; In ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1002/ejoc.200500856