5-Methyl-N2-(4-(4-Methylpiperazin-1-yl)phenyl)pyriMidine-2,4-diaMine

Base Information

Chemical Name:5-Methyl-N2-(4-(4-Methylpiperazin-1-yl)phenyl)pyriMidine-2,4-diaMine
CAS No.:936092-52-3
Molecular Formula:C16H22N6
Molecular Weight:298.391
Hs Code.:
Mol file:936092-52-3.mol

Synonyms:5-Methyl-N2-(4-(4-Methylpiperazin-1-yl)phenyl)pyriMidine-2,4-diaMine;5-Methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidine-2,4-diamine

Suppliers and Price of 5-Methyl-N2-(4-(4-Methylpiperazin-1-yl)phenyl)pyriMidine-2,4-diaMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 5-Methyl-N2-(4-(4-Methylpiperazin-1-yl)phenyl)pyriMidine-2,4-diaMine

Chemical Property:

PSA：71.04000
Density:1.223
LogP:1.86860

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Methyl-N2-(4-(4-Methylpiperazin-1-yl)phenyl)pyriMidine-2,4-diaMine

There total 1 articles about 5-Methyl-N2-(4-(4-Methylpiperazin-1-yl)phenyl)pyriMidine-2,4-diaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 16153-81-4
4-(4-Methyl-piperazino)-anilin

: 14394-70-8
2-chloro-4-amino-5-methylpyrimidine

: 936092-52-3
5-methyl-N₂-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-2,4-diamine

Guidance literature:: 4-(4-Methyl-piperazino)-anilin; 2-chloro-4-amino-5-methylpyrimidine; With acetic acid; at 100 ℃; for 2.5h;

With sodium hydroxide; In water;

Reference yield: 100.0%

: 936092-52-3
5-methyl-N₂-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-2,4-diamine

: 936092-91-0
4-(3-bromo-benzenesulfonyl)-piperidine-1-carboxylic acid benzyl ester

: 4-(3-{5-methyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-ylamino}-benzenesulfonyl)-piperidine-1-carboxylic acid benzyl ester

Guidance literature:: With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 160 ℃; for 0.25h; Microwave irradiation;

Reference yield: 92.0%

: 936092-52-3
5-methyl-N₂-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-2,4-diamine

: 103038-43-3
3-bromo-2-methyl-benzoic acid ethyl ester

: 2-methyl-3-{5-methyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-pyrimidine-4-amino}-benzoic acid ethyl ester

Guidance literature:: With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 160 ℃; for 0.333333h; Microwave irradiation;