Chemical Property of Elobixibat
Chemical Property:
- Boiling Point:969.6±65.0 °C(Predicted)
- PKA:3.20±0.10(Predicted)
- PSA：175.79000
- Density:1.31±0.1 g/cm3(Predicted)
- LogP:8.06540
- XLogP3:7.1
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:9
- Rotatable Bond Count:16
- Exact Mass:695.26989313
- Heavy Atom Count:48
- Complexity:1140
- Purity/Quality:
-
97% *data from raw suppliers
Elobixibat *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CCCCC1(CN(C2=CC(=C(C=C2S(=O)(=O)C1)OCC(=O)NC(C3=CC=CC=C3)C(=O)NCC(=O)O)SC)C4=CC=CC=C4)CCCC
- Isomeric SMILES:CCCCC1(CN(C2=CC(=C(C=C2S(=O)(=O)C1)OCC(=O)N[C@H](C3=CC=CC=C3)C(=O)NCC(=O)O)SC)C4=CC=CC=C4)CCCC
- Recent ClinicalTrials:Elobixibat for Chronic Constipation Without Defecation Desire
- Recent EU Clinical Trials:A Double-blind, Randomised, Placebo-controlled, Phase 3 Trial in Patients with Chronic Idiopathic Constipation to Demonstrate the Efficacy and Safety of Elobixibat 5 mg and 10 mg for 12 Weeks Followed by a 4-week Withdrawal Period
- Recent NIPH Clinical Trials:Efficacy of elobixibat for recovery of loss of defecation desire in patients with chronic constipation. Multicenter, single-group, unblind study.
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Uses
Elobixibat, is an ileal sodium-dependent bile acid transporter ( IBAT) inhibitor, used for the treatment of chronic constipation and irritable bowel syndrome with constipation (IBS-C).
