2-bromo-4,6-dimethyl-3-pyridinol

Base Information

• Chemical Name: 2-bromo-4,6-dimethyl-3-pyridinol
• CAS No.: 1062541-68-7
• Molecular Formula: C₇H₈BrNO
• Molecular Weight: 202.051
• Mol file: 1062541-68-7.mol

Synonyms:2-bromo-4,6-dimethyl-3-pyridinol

Chemical Property of 2-bromo-4,6-dimethyl-3-pyridinol

Chemical Property:

• PSA: 33.12000
• LogP: 2.16650

Purity/Quality:

95+% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-bromo-4,6-dimethyl-3-pyridinol

There total 2 articles about 2-bromo-4,6-dimethyl-3-pyridinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

3-amino-2-bromo-4,6-dimethylpyridine (104829-98-3) → 2-bromo-4,6-dimethyl-3-pyridinol (1062541-68-7)

Guidance literature:

3-amino-2-bromo-4,6-dimethylpyridine; With tetrafluorohydroboric acid; sodium nitrite; In water; at 0 ℃;

With water; at 100 ℃;

DOI:10.1021/ol801983n

Reference yield: 43.0%

→ 2-bromo-4,6-dimethyl-3-pyridinol (1062541-68-7)

Guidance literature:

Reference yield:

1-(2-bromoethoxy)-2,4-dichlorobenzene (6954-77-4) + 2-bromo-4,6-dimethyl-3-pyridinol (1062541-68-7) → C15H14BrCl2NO2 (1355026-52-6)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 40 ℃; for 6h;

DOI:10.1016/j.bmcl.2011.10.096

upstream raw materials:

3-amino-2-bromo-4,6-dimethylpyridine

Downstream raw materials:

C₁₅H₁₄BrCl₂NO₂

Refernces

• 1、 Kumar, Sangit,Johansson, Henrik,Kanda, Takahiro,Engman, Lars,Mueller, Thomas,Bergenudd, Helena,Jonsson, Mats,Pedulli, Gian Franco,Amorati, Riccardo,Valgimigli, Luca. "Catalytic chain-breaking pyridinol antioxidants". supporting information; experimental part. p. 716 - 725. Retrieved 2010/06/13.
• 2、 Kumar, Sangit,Johansson, Henrik,Kanda, Takahiro,Engman, Lars,Mueller, Thomas,Jonsson, Mats,Pedulli, Gian Franco,Petrucci, Silvia,Valgimigli, Luca. "Catalytic chain-breaking pyridinol antioxidants". supporting information; experimental part. p. 4895 - 4898. Retrieved 2009/05/31.