ethyl (5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate

Base Information

Chemical Name:ethyl (5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate
CAS No.:740842-44-8
Molecular Formula:C₁₄H₁₇NO₃
Molecular Weight:247.294
Hs Code.:
Mol file:740842-44-8.mol

Synonyms:ethyl (5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate;(5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-carbamic acid ethyl ester

Suppliers and Price of ethyl (5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate 97%
1g
$ 804.00

Total 2 raw suppliers

Chemical Property of ethyl (5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate

Chemical Property:

PSA：55.40000
LogP:3.23710

Purity/Quality:

97% ^*data from raw suppliers

Ethyl(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate

There total 6 articles about ethyl (5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 741720-99-0
5-(3-ethoxycarbonylamino-phenyl)-pentanoic acid

: 740842-44-8
(5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-carbamic acid ethyl ester

Guidance literature:: With Celite; PPA; In toluene; for 2h; Heating / reflux;

Reference yield:

: 740842-40-4
5-(3-nitrophenyl)pent-4-ynoic acid methyl ester

: 740842-44-8
(5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/C / methanol

2: i-Pr₂NH / CH₂Cl₂

3: aq. LiOH / methanol; tetrahydrofuran

4: polyphosphoric acid; celite / toluene

With lithium hydroxide; PPA; Celite; hydrogen; diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1016/j.bmcl.2006.07.064

Reference yield:

: 6089-09-4
4-pentynoic acid

: 740842-44-8
(5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 75 percent / sulfuric acid

2: Pd(OAc)2; PPh₃; CuI / HNEt₂ / dimethylformamide

3: H₂ / Pd/C / methanol

4: i-Pr₂NH / CH₂Cl₂

5: aq. LiOH / methanol; tetrahydrofuran

6: polyphosphoric acid; celite / toluene

With palladium diacetate; lithium hydroxide; copper(l) iodide; PPA; Celite; sulfuric acid; hydrogen; diisopropylamine; triphenylphosphine; palladium on activated charcoal; diethylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene; 2: Sonagashira coupling;
DOI:10.1016/j.bmcl.2006.07.064