6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER

Base Information

• Chemical Name: 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER
• CAS No.: 228728-86-7
• Molecular Formula: C₁₃H₁₂ClNO₃
• Molecular Weight: 265.696
• Hs Code.: 2933499090
• Mol file: 228728-86-7.mol

Synonyms:6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER;ETHYL 6-CHLORO-4-HYDROXY-8-METHYL-3-QUINOLINECARBOXYLATE;ETHYL 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLATE

Chemical Property of 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER

Chemical Property:

• Vapor Pressure: 1.16E-06mmHg at 25°C
• Boiling Point: 401.7°C at 760 mmHg
• Flash Point: 196.8°C
• PSA: 59.42000
• Density: 1.312g/cm³
• LogP: 3.07890

Purity/Quality:

98%Min ^*data from raw suppliers

6-Chloro-4-hydroxy-8-methylquinoline-3-carboxylic acid ethyl ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER

There total 1 articles about 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 2-ethoxymethylenemalonate (87-13-8) + 4-chloro-2-methylbenzeneamine (95-69-2) → 6-chloro-3-ethoxycarbonyl-8-methyl-4(1H)-quinolone (175134-96-0,228728-86-7)

Guidance literature:

Reference yield: 40.0%

ethyl 6-chloro-4-hydroxy-8-methyl-3-quinolinecarboxylate (228728-86-7,175134-96-0) + 4-chlorobenzylamine (104-86-9) → 6-chloro-N-[(4-chlorophenyl)methyl]-4-hydroxy-8-methyl-3-quinolinecarboxamide

Guidance literature:

at 190 ℃; for 3h;

upstream raw materials:

diethyl 2-ethoxymethylenemalonate

4-chloro-2-methylbenzeneamine

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