Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate

Base Information

Chemical Name:Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate
CAS No.:950259-82-2
Molecular Formula:C11H9FN2O3
Molecular Weight:236.202
Hs Code.:
Mol file:950259-82-2.mol

Synonyms:Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate;5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate
1g
$ 565.00

Heterocyclics
Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate 95%
1g
$ 175.00

Atlantic Research Chemicals
Ethyl5-(4-Fluorophenyl)-1,3,4-oxadiazole-2-carboxylate 95%
1gm:
$ 187.33

Atlantic Research Chemicals
Ethyl5-(4-Fluorophenyl)-1,3,4-oxadiazole-2-carboxylate 95%
5gm:
$ 798.81

Alichem
Ethyl5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate
5g
$ 1007.00

Alichem
Ethyl5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate
1g
$ 329.68

AK Scientific
Ethyl5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate
250mg
$ 533.00

AK Scientific
Ethyl5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate
100mg
$ 524.00

Total 7 raw suppliers

Chemical Property of Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate

Chemical Property:

Boiling Point:338.3±44.0 °C(Predicted)
PKA:-5.09±0.11(Predicted)
PSA：65.22000
Density:1.293±0.06 g/cm3(Predicted)
LogP:2.05240

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate

There total 10 articles about Ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 2251-76-5
2-(4-fluorophenyl)-2-oxoacetic acid

: (1-diazo-2-ethoxy-2-oxoethyl)(2-(2-ethoxy-2-oxoethoxy)carbonylphenyl)iodonium trifluoromethanesulfonate

: 950259-82-2
ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate

Guidance literature:: With 1,2,3,4-tetrakis(carbazol-9-yl)-5,6-dicyanobenzene; In dichloromethane; at 25 ℃; Inert atmosphere; Irradiation; Schlenk technique; Sealed tube;
DOI:10.1021/acs.orglett.0c03663

Reference yield: 81.0%

: C₁₆H₁₆F₃IN₂O₉S

: 459-57-4
4-fluorobenzaldehyde

: 950259-82-2
ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate

Guidance literature:: In dichloromethane; at 20 ℃; for 12h; Irradiation;

Reference yield: 55.0%

: C₁₁H₁₀F₃IN₂O₅S

: 459-57-4
4-fluorobenzaldehyde

: 950259-82-2
ethyl 5-(4-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate

Guidance literature:: C₁₁H₁₀F₃IN₂O₅S; 4-fluorobenzaldehyde; With 2-pentafluorophenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; tert-butyl alcohol; In 1,2-dichloro-ethane; at 0 ℃; for 0.0833333h; Schlenk technique; Sealed tube; Inert atmosphere;

With N,N,N,N,-tetramethylethylenediamine; In 1,2-dichloro-ethane; at 0 ℃; for 20h; Schlenk technique; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.orglett.1c01128