4-Fluoro-a-oxo-benzeneacetic acid

Base Information

Chemical Name:4-Fluoro-a-oxo-benzeneacetic acid
CAS No.:2251-76-5
Molecular Formula:C8H5FO3
Molecular Weight:168.124
Hs Code.:2918300090
Mol file:2251-76-5.mol

Synonyms:4-Fluoro-a-oxo-benzeneacetic acid;2-(4-fluorophenyl)-2-oxoacetic acid

Suppliers and Price of 4-Fluoro-a-oxo-benzeneacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-?Fluoro-?α-?oxobenzeneaceticAcid
100mg
$ 55.00

Rieke Metals
2-(4-FLUOROPHENYL)-2-OXOACETICACID
1g
$ 809.00

Rieke Metals
2-(4-FLUOROPHENYL)-2-OXOACETICACID
5g
$ 1943.00

Heterocyclics
4-fluoro-α-oxo-Benzeneaceticacid
1g
$ 72.00

Heterocyclics
4-fluoro-α-oxo-Benzeneaceticacid
5g
$ 295.00

Crysdot
2-(4-Fluorophenyl)-2-oxoaceticacid 95+%
5g
$ 306.00

Crysdot
2-(4-Fluorophenyl)-2-oxoaceticacid 95+%
25g
$ 1164.00

Crysdot
2-(4-Fluorophenyl)-2-oxoaceticacid 95+%
10g
$ 581.00

Chemenu
2-(4-Fluorophenyl)-2-oxoaceticacid 95%
25g
$ 957.00

Chemenu
2-(4-Fluorophenyl)-2-oxoaceticacid 95%
10g
$ 550.00

Total 14 raw suppliers

Chemical Property of 4-Fluoro-a-oxo-benzeneacetic acid

Chemical Property:

Melting Point:98-100 °C
Boiling Point:113-114 °C(Press: 15 Torr)
PKA:2.11±0.54(Predicted)
PSA：54.37000
Density:1.403±0.06 g/cm3(Predicted)
LogP:1.09300
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-?Fluoro-?α-?oxobenzeneaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4-?Fluoro-?α-?oxobenzeneacetic Acid is involved in preparation of aryl ketones via palladium-catalyzed decarboxylative acylation of arenes with a-oxocarboxylic acids.

Technology Process of 4-Fluoro-a-oxo-benzeneacetic acid

There total 23 articles about 4-Fluoro-a-oxo-benzeneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1813-94-1
ethyl 4-fluorobenzoylformate

: 2251-76-5
2-(4-fluorophenyl)-2-oxoacetic acid

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1039/c6ob00739b

Reference yield: 94.7%

: 94593-83-6
p-fluoro-2-(hydroxyimino)-2-phenylacetonitrile

: 2251-76-5
2-(4-fluorophenyl)-2-oxoacetic acid

Guidance literature:: With sulfuric acid; at 100 ℃; for 7h;

Reference yield: 94.0%

: 32222-45-0,52923-25-8,52950-15-9,395-33-5
4-fluoromandelic acid

: 2251-76-5
2-(4-fluorophenyl)-2-oxoacetic acid

Guidance literature:: With 2-azatricyclo[3.3.1.1^3,7]decan-2-ol; sodium nitrite; In acetonitrile; at 20 ℃; for 2h;
DOI:10.1021/acs.joc.0c01302