Didestriazole Anastrozole Dimer Impurity

Base Information

Chemical Name:Didestriazole Anastrozole Dimer Impurity
CAS No.:918312-71-7
Molecular Formula:C₂₆H₂₉N₃
Molecular Weight:383.536
Hs Code.:
European Community (EC) Number:680-874-3
DSSTox Substance ID:DTXSID80581004
Mol file:918312-71-7.mol

Synonyms:Didestriazole Anastrozole Dimer Impurity;918312-71-7;2,3-bis[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile;Di-Destriazole Anastrozole DiMer IMpurity;SCHEMBL4621304;DTXSID80581004;2,2'-[(2-Cyanopropane-1,2-diyl)bis(5-methyl-3,1-phenylene)]bis(2-methylpropanenitrile)

Suppliers and Price of Didestriazole Anastrozole Dimer Impurity

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 10 raw suppliers

Chemical Property of Didestriazole Anastrozole Dimer Impurity

Chemical Property:

PSA：71.37000
LogP:5.92974
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate, Dimethyl Sulfoxide
XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:383.236147938
Heavy Atom Count:29
Complexity:736

Purity/Quality:: > 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)C(C)(C)C#N)CC(C)(C#N)C2=CC(=CC(=C2)C(C)(C)C#N)C
Uses Anastrozole Dimer Impurity (A637440) derivative. Anastrozole Dimer Impurity (A637440) derivative. Anastrozole Impurity A

Technology Process of Didestriazole Anastrozole Dimer Impurity

There total 2 articles about Didestriazole Anastrozole Dimer Impurity which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.1%

: C₂₃H₂₃N₃

: 74-88-4
methyl iodide

: 918312-71-7
2,3-bis(3-(1-cyano-1-methylethyl)-5-methylphenyl)-2-methylpropanenitrile

Guidance literature:: C₂₃H₂₃N₃; With lithium diisopropyl amide; In tetrahydrofuran; at -50 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at -20 ℃; for 2h;

Reference yield: 79.7%

: 120512-36-9
2-(3-bromomethyl-5-methylphenyl)-2-methylpropionitrile

: 2-[3-(1-cyanoethyl)-5-methylphenyl]-2-methylpropanenitrile

: 918312-71-7
2,3-bis(3-(1-cyano-1-methylethyl)-5-methylphenyl)-2-methylpropanenitrile

Guidance literature:: 2-[3-(1-cyanoethyl)-5-methylphenyl]-2-methylpropanenitrile; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 5 ℃; for 0.25h; Inert atmosphere;

2-(3-bromomethyl-5-methylphenyl)-2-methylpropionitrile; In N,N-dimethyl-formamide; at 0 - 5 ℃; Inert atmosphere;