6-Amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Base Information

Chemical Name:6-Amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS No.:100644-68-6
Molecular Formula:C₂₇H₂₇N₅O₆
Molecular Weight:517.541
Hs Code.:
DSSTox Substance ID:DTXSID501107769

Synonyms:100644-68-6;6-Amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine;DTXSID501107769;F86363;[(2R,3S,5R)-5-(6-amino-4-methoxypyrazolo[3,4-d]pyrimidin-1-yl)-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate;1-[2-Deoxy-3,5-bis-O-(4-methylbenzoyl)-beta-D-erythro-pentofuranosyl]-4-methoxy-1H-pyrazolo[3,4-d]pyrimidin-6-amine;6-AMINO-4-METHOXY-1-(2-DEOXY-3,5-DI-O-(P-TOLUOYL)-BETA-D-RIBOFURANOSYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE

Suppliers and Price of 6-Amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 6-Amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:9
Exact Mass:517.19613360
Heavy Atom Count:38
Complexity:818

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)OCC2C(CC(O2)N3C4=C(C=N3)C(=NC(=N4)N)OC)OC(=O)C5=CC=C(C=C5)C
Isomeric SMILES:CC1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H](C[C@@H](O2)N3C4=C(C=N3)C(=NC(=N4)N)OC)OC(=O)C5=CC=C(C=C5)C

Technology Process of 6-Amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

There total 6 articles about 6-Amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 3056-12-0,3601-89-6,4330-21-6,52304-86-6,141846-57-3
2-deoxy-3,5-di-O-(p-toluoyl)-α-D-erythropentofuranosyl chloride

: 100644-67-5
6-amino-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

: 109737-90-8
6-amino-1-[2'-deoxy-3',5'-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

: 100644-68-6
6-amino-1-<2'-deoxy-3',5'-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl>-4-methoxy-1H-pyrazolo<3,4-d>pyrimidine

Guidance literature:: With potassium hydroxide; Tris(3,6-dioxaheptyl)amine; In acetonitrile; for 0.5h; Ambient temperature;
DOI:10.1002/hlca.19880710410

Reference yield: 52.0%

: 4330-21-6
2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

: 100644-67-5
6-amino-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

: 6-amino-4-methoxy-1-(2-deoxy-3,5-di-(O-p-toluoyl)-α-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

: 100644-68-6
6-amino-1-<2'-deoxy-3',5'-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl>-4-methoxy-1H-pyrazolo<3,4-d>pyrimidine

Guidance literature:: 6-amino-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine; With Tris(3,6-dioxaheptyl)amine; potassium hydroxide; In acetonitrile; for 0.25h;

2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride; In acetonitrile; at 20 ℃; for 0.5h;
DOI:10.3390/molecules24050983

Reference yield: 37.0%

: 3056-12-0,3601-89-6,4330-21-6,52304-86-6,141846-57-3
2-deoxy-3,5-di-O-(p-toluoyl)-α-D-erythropentofuranosyl chloride

: 100644-67-5
6-amino-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

: 109737-90-8
6-amino-1-[2'-deoxy-3',5'-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

: 100644-68-6
6-amino-1-<2'-deoxy-3',5'-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl>-4-methoxy-1H-pyrazolo<3,4-d>pyrimidine

: 6-amino-1-(2'-deoxy-3',5'-di-O-(p-toluoyl)-α-D-erythro-pentofuranosyl)-4-methoxy-1H-pyrazolo<3,4-d>pyrimidine

Guidance literature:: With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; water; for 0.0333333h; Ambient temperature;
DOI:10.1002/hlca.19860690714