BENZYL-N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE

Base Information Edit

Chemical Name:BENZYL-N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE
CAS No.:128753-68-4
Molecular Formula:C13H21ClNOP
Molecular Weight:273.743
Hs Code.:
DSSTox Substance ID:DTXSID00404640
Mol file:128753-68-4.mol

Synonyms:BENZYL-N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE

Suppliers and Price of BENZYL-N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of BENZYL-N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE Edit

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:273.1049290
Heavy Atom Count:17
Complexity:200

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N(C(C)C)P(OCC1=CC=CC=C1)Cl

Technology Process of BENZYL-N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE

There total 4 articles about BENZYL-N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 76101-29-6
benzyloxy dichlorophosphine

: 108-18-9
diisopropylamine

: 128753-68-4
(benzyloxy)chloro(diisopropylamino)phosphane

Guidance literature:: With triethylamine; In diethyl ether; at -20 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2013.07.052

Reference yield:

: 100-51-6,185532-71-2
benzyl alcohol

: 128753-68-4
(benzyloxy)chloro(diisopropylamino)phosphane

Guidance literature:: Multi-step reaction with 2 steps

1: PCl₃ / acetonitrile / 20 h / Ambient temperature

2: diisopropylamine / diethyl ether / 14 h / Ambient temperature

With diisopropylamine; phosphorus trichloride; In diethyl ether; acetonitrile;
DOI:10.1021/jo00303a028