Cupric fluoride

Base Information

• Chemical Name: Cupric fluoride
• CAS No.: 7789-19-7
• Molecular Formula: CuF2
• Molecular Weight: 101.54
• DSSTox Substance ID: DTXSID80894782
• Wikipedia: Copper(II) fluoride,Copper(II)_fluoride
• Wikidata: Q419686
• Mol file: 7789-19-7.mol

Synonyms:Cupric fluoride;Copper(II) fluoride;difluorocopper;CuF2;Copper fluoride (CuF2);MFCD00010977;copper(II) flouride;UNII-ML04XYE5C1;Copper(II) fluoride, 98%;DTXSID80894782;EINECS 232-147-3;AKOS015915951;FT-0624058;Q419686

Chemical Property of Cupric fluoride

Chemical Property:

• Appearance/Colour: Blue powder
• Vapor Pressure: 922mmHg at 25°C
• Melting Point: 950 °C (dec.)(lit.)
• Boiling Point: 950oC
• PSA: 0.00000
• Density: 4.23 g/mL at 25 °C(lit.)
• LogP: 0.83790
• Water Solubility.: SOLUBLE IN COLD WATER
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 100.926403
• Heavy Atom Count: 3
• Complexity: 2.8

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s): C,Xi
• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S24/25:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Metals, Inorganic Compounds
• Canonical SMILES: F[Cu]F
• Recent ClinicalTrials: Efficacy Study of Herbal Formula CUF2 to Treat Childhood Asthma

Refernces

Synthesis of 2-aryl-3-trifluoromethylquinolines using (E)-trimethyl(3,3,3- trifluoroprop-1-enyl)silane

10.1021/jo400859s

The study presents a novel synthetic method for the production of 2-aryl-3-trifluoromethylquinolines, which are compounds of interest in pharmaceutical, agrochemical, and high-performance material sectors due to their significant roles. The researchers utilized a Hiyama cross-coupling reaction involving (E)-trimethyl(3,3,3-trifluoroprop-1-enyl)silane and 2-iodoaniline, facilitated by copper(II) fluoride and 2,2′-bipyridyl as a fluoride source and ligand, respectively. This reaction yielded (E)-2-(3,3,3-trifluoroprop-1-enyl)aniline without the need for amino group protection. Subsequently, an oxidative cyclization reaction with aryl aldehydes in the presence of a copper(I) salt catalyst, specifically [Cu(OTf)]2·C6H6, led to the formation of the target quinolines. The study's purpose was to develop an efficient synthetic protocol to access 3-trifluoromethylquinolines, which are challenging to synthesize using conventional methods, and to expand the library of such compounds for potential therapeutic applications.