PYRAZOLO[1,5-A]PYRIDIN-5-YLMETHANAMINE(STRID308183532)

Base Information

Chemical Name:PYRAZOLO[1,5-A]PYRIDIN-5-YLMETHANAMINE(STRID308183532)
CAS No.:1313727-03-5
Molecular Formula:C8H9N3
Molecular Weight:147.18
Hs Code.:
Mol file:1313727-03-5.mol

Synonyms:PYRAZOLO[1,5-A]PYRIDIN-5-YLMETHANAMINE(STRID308183532);pyrazolo[1,5-a]pyridin-5-ylmethanamine;Pyrazolo[1,5-a]pyridine-5-methanamine

Suppliers and Price of PYRAZOLO[1,5-A]PYRIDIN-5-YLMETHANAMINE(STRID308183532)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemBridge Corporation
(pyrazolo[1,5-a]pyridin-5-ylmethyl)amine 95%
250 mg
$ 170.00

Total 2 raw suppliers

Chemical Property of PYRAZOLO[1,5-A]PYRIDIN-5-YLMETHANAMINE(STRID308183532)

Chemical Property:

PSA：43.32000
LogP:1.49330

Purity/Quality:

97% ^*data from raw suppliers

(pyrazolo[1,5-a]pyridin-5-ylmethyl)amine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of PYRAZOLO[1,5-A]PYRIDIN-5-YLMETHANAMINE(STRID308183532)

There total 8 articles about PYRAZOLO[1,5-A]PYRIDIN-5-YLMETHANAMINE(STRID308183532) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₈H₇N₅

: 1313727-03-5
pyrazolo[1,5-a]pyridin-5-ylmethanamine

Guidance literature:: With ammonium hydroxide; triphenylphosphine; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm500510f

Reference yield:

: 586-95-8
pyridine-4-methanol

: 1313727-03-5
pyrazolo[1,5-a]pyridin-5-ylmethanamine

Guidance literature:: Multi-step reaction with 7 steps

1: triethylamine / dichloromethane / 4 h / 0 - 20 °C

2: acetonitrile / 24 h / 40 °C

3: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

4: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 20 °C

5: sulfuric acid / 24 h / 80 °C

6: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0 °C

7: ammonium hydroxide; triphenylphosphine / tetrahydrofuran / 20 °C

With ammonium hydroxide; sulfuric acid; diphenyl phosphoryl azide; tetrabutyl ammonium fluoride; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm500510f

Reference yield:

: 117423-41-3
4-((tert-butyldimethylsilyloxy)methyl)pyridine

: 1313727-03-5
pyrazolo[1,5-a]pyridin-5-ylmethanamine

Guidance literature:: Multi-step reaction with 6 steps

1: acetonitrile / 24 h / 40 °C

2: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 20 °C

4: sulfuric acid / 24 h / 80 °C

5: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0 °C

6: ammonium hydroxide; triphenylphosphine / tetrahydrofuran / 20 °C

With ammonium hydroxide; sulfuric acid; diphenyl phosphoryl azide; tetrabutyl ammonium fluoride; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm500510f