2-Cyclopentylacetamide

Base Information

• Chemical Name: 2-Cyclopentylacetamide
• CAS No.: 933-04-0
• Molecular Formula: C7H13NO
• Molecular Weight: 127.186
• Hs Code.: 2924299090
• European Community (EC) Number: 821-461-1
• ChEMBL ID: CHEMBL4533263
• DSSTox Substance ID: DTXSID20593661
• Nikkaji Number: J829.138A
• Wikidata: Q82488181
• Mol file: 933-04-0.mol

Synonyms:2-cyclopentylacetamide;933-04-0;cyclopentylacetamide;carbamoylmethylcyclopentane;SCHEMBL302210;CHEMBL4533263;DTXSID20593661;OXRCIXHTUHZNRY-UHFFFAOYSA-N;2-cyclopentylacetamide, AldrichCPR;AKOS005280590;TS-01667;DB-313919;EN300-30766;G31011;Z33546662

Chemical Property of 2-Cyclopentylacetamide

Chemical Property:

• PSA: 44.08000
• LogP: 2.20170
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 127.099714038
• Heavy Atom Count: 9
• Complexity: 106

Purity/Quality:

97% ^*data from raw suppliers

2-Cyclopentylacetamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C1)CC(=O)N

Technology Process of 2-Cyclopentylacetamide

There total 6 articles about 2-Cyclopentylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-cyclopentylacetic acid (1123-00-8) → 2-cyclopentylacetamide (933-04-0)

Guidance literature:

(-)-1α-cyclopentaneacetic acid; With Carbonyldiimidazole; In dichloromethane; at 22 ℃; for 1h; Inert atmosphere;

With ammonium hydroxide; In dichloromethane; water monomer; at 0 - 20 ℃;

DOI:10.1016/j.tet.2019.02.063

Reference yield: 82.0%

2-cyclopentylacetonitrile (5732-87-6) → 2-cyclopentylacetamide (933-04-0)

Guidance literature:

With Wilkinson's catalyst; Acetaldehyde oxime; In toluene; at 110 ℃; for 4h;

DOI:10.15227/orgsyn.089.0066

Reference yield: 46.0%

2-cyclopentylacetyl chloride (1122-99-2) → 2-cyclopentylacetamide (933-04-0)

Guidance literature:

With ammonia; In dichloromethane; at 0 - 25 ℃; for 0.333333h; Inert atmosphere;

upstream raw materials:

2-cyclopentyl-malonamic acid

2-cyclopentylacetic acid

2-cyclopentylacetyl chloride

2-cyclopentylacetonitrile

Downstream raw materials:

2-cyclopentylethan-1-amine

2-cyclopentylacetonitrile