2-aMino-5-chloronicotinaMide

Base Information

Chemical Name:2-aMino-5-chloronicotinaMide
CAS No.:58483-97-9
Molecular Formula:C6H6ClN3O
Molecular Weight:171.586
Hs Code.:
Mol file:58483-97-9.mol

Synonyms:2-aMino-5-chloronicotinaMide

Suppliers and Price of 2-aMino-5-chloronicotinaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Amino-5-chloronicotinamide 97%
1g
$ 668.00

Alichem
2-Amino-5-chloronicotinamide
1g
$ 549.44

AccelPharmtech
2-amino-5-chloro-3-Pyridinecarboxamide 97.00%
25G
$ 4320.00

AccelPharmtech
2-amino-5-chloro-3-Pyridinecarboxamide 97.00%
5G
$ 2330.00

AccelPharmtech
2-amino-5-chloro-3-Pyridinecarboxamide 97.00%
1G
$ 2070.00

Total 6 raw suppliers

Chemical Property of 2-aMino-5-chloronicotinaMide

Chemical Property:

PSA：82.99000
LogP:1.88150

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-5-chloronicotinamide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-aMino-5-chloronicotinaMide

There total 4 articles about 2-aMino-5-chloronicotinaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 26163-03-1
2-amino-3-bromo-5-chloropyridine

: 58483-97-9
2-amino-5-chloropyridine-3-carboxamide

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassiumhexacyanoferrate(II) trihydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In water; tert-butyl alcohol; at 120 ℃; for 0.166667h; under 8274.59 Torr; Microwave irradiation;
DOI:10.1021/jm401249c

Reference yield: 38.0%

: 13438-65-8
2-aminopyridine-3-carboxamide

: 58483-97-9
2-amino-5-chloropyridine-3-carboxamide

Guidance literature:: With hydrogenchloride; dihydrogen peroxide; In water; at 0 - 60 ℃; for 1h;
DOI:10.1021/acs.jmedchem.5b01528

Reference yield:

: 5345-47-1
2-aminopyridin-3-carboxylic acid

: 58483-97-9
2-amino-5-chloropyridine-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; ammonium chloride / N,N-dimethyl-formamide / 12 h / 20 °C

2: hydrogenchloride; dihydrogen peroxide / 6 h / 60 °C

With hydrogenchloride; dihydrogen peroxide; ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;
DOI:10.3390/molecules25235693