3-Bromo-1-tosylpiperidin-4-one

Base Information

Chemical Name:3-Bromo-1-tosylpiperidin-4-one
CAS No.:171009-41-9
Molecular Formula:C12H14BrNO3S
Molecular Weight:332.218
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50408012
Mol file:171009-41-9.mol

Synonyms:3-Bromo-1-tosylpiperidin-4-one;171009-41-9;1-tosyl-3-bromo-piperidin-4-one;3-bromo-1-(4-methylphenyl)sulfonylpiperidin-4-one;DTXSID50408012;AKOS016013881;3-BROMO-1-(TOLUENE-4-SULFONYL)-PIPERIDIN-4-ONE

Suppliers and Price of 3-Bromo-1-tosylpiperidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Bromo-1-tosylpiperidin-4-one 95+%
1g
$ 510.00

Chemenu
3-bromo-1-tosylpiperidin-4-one 95%
1g
$ 482.00

American Custom Chemicals Corporation
3-BROMO-1-(TOLUENE-4-SULFONYL)-PIPERIDIN-4-ONE 95.00%
5MG
$ 500.23

Alichem
3-Bromo-1-tosylpiperidin-4-one
1g
$ 416.00

Total 6 raw suppliers

Chemical Property of 3-Bromo-1-tosylpiperidin-4-one

Chemical Property:

PSA：62.83000
LogP:2.74070
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:330.98778
Heavy Atom Count:18
Complexity:410

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

3-Bromo-1-tosylpiperidin-4-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CCC(=O)C(C2)Br

Technology Process of 3-Bromo-1-tosylpiperidin-4-one

There total 4 articles about 3-Bromo-1-tosylpiperidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 33439-27-9
N-tosyl-4-piperidone

: 171009-41-9
O-ethyl-S-(4-oxo-1-tosylpiperidin-3-yl)carbonodithioate

Guidance literature:: With bromine; In dichloromethane; -4 deg C, 90 min; 0 deg C, 30 min; room temperature, 1 h;

Reference yield:

: 1332708-91-4
C₁₅H₂₃NO₃SSi

: 171009-41-9
O-ethyl-S-(4-oxo-1-tosylpiperidin-3-yl)carbonodithioate

Guidance literature:: With N-Bromosuccinimide; In tetrahydrofuran; at 0 ℃; for 0.0833333h;
DOI:10.1021/ol403310f

Reference yield:

: 41979-39-9
4-piperidone hydrochloride

: 171009-41-9
O-ethyl-S-(4-oxo-1-tosylpiperidin-3-yl)carbonodithioate

Guidance literature:: Multi-step reaction with 2 steps

1: polymer supported DMAP / CH₂Cl₂

2: polymer supported pyridinium bromide perbromide / toluene / 10 °C

With polymer supported DMAP; polymer supported pyridinium bromide perbromide; In dichloromethane; toluene;
DOI:10.1039/a805997g