1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-

Base Information

Chemical Name:1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-
CAS No.:79286-81-0
Molecular Formula:C16H19FN4O3
Molecular Weight:334.35
Hs Code.:
DSSTox Substance ID:DTXSID901000373
ChEMBL ID:CHEMBL288250

Synonyms:BRN 5617195;1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-;79286-81-0;CHEMBL288250;SCHEMBL11165875;DTXSID901000373;LS-95943;1-Ethyl-6-fluoro-7-[3-(methylamino)pyrrolidin-1-yl]-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

Suppliers and Price of 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-

Chemical Property:

Vapor Pressure:2.81E-13mmHg at 25°C
Boiling Point:557.8°Cat760mmHg
Flash Point:291.1°C
Density:1.42g/cm³
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:334.14411864
Heavy Atom Count:24
Complexity:555

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCC(C3)NC)F)C(=O)O

Technology Process of 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-

There total 1 articles about 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79286-87-6,550370-77-9,550370-81-5
(RS)-3-(acetyl-methyl-amino)-pyrrolidine

: 79286-81-0
1-ethyl-6-fluoro-1,4-dihydro-7-(3-methylamino-1-pyrrolidinyl)-4-oxo-1,8-naphthyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / Et₃N / 100 - 110 °C

2: 71 percent / aq. NaOH / 4 h / Heating

With sodium hydroxide; triethylamine;
DOI:10.1021/jm00378a004