5-Aminoindan-1-one

Base Information

• Chemical Name: 5-Aminoindan-1-one
• CAS No.: 3470-54-0
• Molecular Formula: C9H9NO
• Molecular Weight: 147.177
• Hs Code.: 2922399090
• Mol file: 3470-54-0.mol

Synonyms:1-Indanone,5-amino- (7CI,8CI);5-Amino-1-oxoindan;5-Amino-1-oxoindane;5-Amino-2,3-dihydro-1H-inden-1-one;5-Amino-2,3-dihydroinden-1-one;5-Aminoindan-1-one;NSC 225093;

Chemical Property of 5-Aminoindan-1-one

Chemical Property:

• Vapor Pressure: 6.57E-05mmHg at 25°C
• Melting Point: 184-186 ºC
• Refractive Index: 1.65
• Boiling Point: 344.5 °C at 760 mmHg
• PKA: 2.12±0.20(Predicted)
• Flash Point: 162.1 °C
• PSA: 43.09000
• Density: 1.254 g/cm³
• LogP: 1.97890
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

5-Aminoindan-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xn,Xi,T
• Statements: 20/21/22-52/53-25-52
• Safety Statements: 36/37-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Aminoindan-1-one

There total 7 articles about 5-Aminoindan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-((diphenylmethylene)amino)-2,3-dihydro-1H-inden-1-one → 5-aminoindan-1-one (3470-54-0)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; methanol; at 25 ℃;

DOI:10.1021/acs.jmedchem.1c01436

Reference yield: 90.0%

2-methyl-2-propanyl (1-oxo-2,3-dihydro-1H-inden-5-yl)carbamate (1116358-96-3) → 5-aminoindan-1-one (3470-54-0)

Guidance literature:

2-methyl-2-propanyl (1-oxo-2,3-dihydro-1H-inden-5-yl)carbamate; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;

With sodium hydrogencarbonate; In dichloromethane; water;

DOI:10.1016/j.ejmech.2008.02.026

Reference yield:

5-acetamido-1-indanone (58161-35-6) → 5-aminoindan-1-one (3470-54-0)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jm00226a004 DOI:10.1039/b102779b

upstream raw materials:

5-acetamido-1-indanone

5-acetamidoindane

3-acetylaminobenzene propanoic acid

3-Acetaminohydrozimtsaeuremethylester

Downstream raw materials:

5-cyano-1-indanone

5-iodoindan-1-one

5-benzamidoindan-1-one

N-(2-benzylidene-1-oxoindan-5-yl)benzamide