formosanin C

Base Information

• Chemical Name: formosanin C
• CAS No.: 50773-42-7
• Molecular Formula: C51H82 O20
• Molecular Weight: 1015.2
• Mol file: 50773-42-7.mol

Synonyms:Asperin;Diosgenin 3-O-a-L-rhamnopyranosyl-(1®2)-[a-L-rhamnopyranosyl-(1®4)-a-L-rhamnopyranosyl-(1®4)]-b-D-glucopyranoside; Diosgenin3-O-a-L-rhamnopyranosyl-(1®4)-a-L-rhamnopyranosyl-(1®4)-[a-L-rhamnopyranosyl-(1®2)]-b-D-glucopyranoside; Formosanin C;NSC 306864; Parissaponin Pb; Parrisaponin; Pb; Saponin P-d, from Alliumfistulosum; Saponin Pb

Chemical Property of formosanin C

Chemical Property:

• Melting Point: 222～231℃
• PKA: 12?+-.0.70(Predicted)
• PSA: 294.60000
• Density: 1.43±0.1 g/cm3(Predicted)
• LogP: 0.09350

Purity/Quality:

≥98% ^*data from raw suppliers

FormosaninC 99.28% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of formosanin C

There total 6 articles about formosanin C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C117H130O30 → (3β,17α,25R)-spirost-5-ene-3,17-diol-3-O-α-L-rhamnopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->4)-[α-L-rhamnopyranosyl-(1->2)]-β-D-glucopyranoside (50773-42-7)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; methanol; at 40 ℃; for 15h; Inert atmosphere;

DOI:10.1002/cjoc.201900126

Reference yield:

C88H116O28 → (3β,17α,25R)-spirost-5-ene-3,17-diol-3-O-α-L-rhamnopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->4)-[α-L-rhamnopyranosyl-(1->2)]-β-D-glucopyranoside (50773-42-7)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; methanol; at 45 ℃; for 18h;

DOI:10.1016/j.carres.2021.108359

Reference yield:

C75H106O28 → (3β,17α,25R)-spirost-5-ene-3,17-diol-3-O-α-L-rhamnopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->4)-[α-L-rhamnopyranosyl-(1->2)]-β-D-glucopyranoside (50773-42-7)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/S0040-4039(99)01839-0

upstream raw materials:

C₅₈H₉₆O₂₆

Methyl proto-Pb

Downstream raw materials:

D-Glucose

L-rhamnose

Refernces

• 1、 Ehianeta, Teddy Stephen,Shen, Dacheng,Xu, Peng,Yu, Biao. "Synthesis of spirostanol saponins via gold(I)-catalyzed glycosylation in the presence of Ga(OTf)3, In(OTf)3, or HOTf". supporting information. p. 827 - 833. Retrieved 2019/07/22.
• 2、 Yu, Biao,Yu, Hai,Hui, Yongzheng,Han, Xiuwen. "Synthesis of a group of diosgenyl saponins by a one-pot sequential glycosylation". . p. 8591 - 8594. Retrieved 2007/10/03.