2-(4-Chlorophenyl)-3-hydroxypropanoic acid

Base Information

Chemical Name:2-(4-Chlorophenyl)-3-hydroxypropanoic acid
CAS No.:16864-90-7
Molecular Formula:C₉H₉ClO₃
Molecular Weight:200.622
Hs Code.:
European Community (EC) Number:865-941-9
Mol file:16864-90-7.mol

Synonyms:2-(4-chlorophenyl)-3-hydroxypropanoic acid;16864-90-7;SCHEMBL12985331;CKIPXLZSJUHFDD-UHFFFAOYSA-N;AKOS022646619;2-(4-chlorophenyl)-3-hydroxypropanoicacid;3-hydroxyl-2-(p-chlorophenyl) propionic acid;2-(4-Chloro-phenyl)-3-hydroxy-propionic acid;EN300-207475;Z1508925263

Suppliers and Price of 2-(4-Chlorophenyl)-3-hydroxypropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-chlorophenyl)-3-hydroxypropanoicAcid
50mg
$ 350.00

AK Scientific
2-(4-Chlorophenyl)-3-hydroxypropanoicacid
500mg
$ 1001.00

AK Scientific
2-(4-Chlorophenyl)-3-hydroxypropanoicacid
250mg
$ 673.00

Total 4 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-3-hydroxypropanoic acid

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:200.0240218
Heavy Atom Count:13
Complexity:176

Purity/Quality:

95% ^*data from raw suppliers

2-(4-chlorophenyl)-3-hydroxypropanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C(CO)C(=O)O)Cl

Technology Process of 2-(4-Chlorophenyl)-3-hydroxypropanoic acid

There total 6 articles about 2-(4-Chlorophenyl)-3-hydroxypropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.1%

: 109135-06-0
methyl 2-(4-chlorophenyl)-3-hydroxypropanoate

: 16864-90-7,195502-93-3,195502-94-4
2-(4-chlorophenyl)-3-hydroxypropanoic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 0 - 20 ℃; for 2.5h;
DOI:10.1016/j.tet.2022.132653

Reference yield: 12.5%

: 86762-37-0
2-(4-Chloro-phenyl)-3-hydroxy-propionic acid ethyl ester

: 16864-90-7,195502-93-3,195502-94-4
2-(4-chlorophenyl)-3-hydroxypropanoic acid

Guidance literature:: With sodium hydroxide; In ethanol; 1) reflux, 5 min, 2) R_.T_., 3 h;

Reference yield:

: 14062-24-9
4-chloro-benzeneacetic acid, ethyl ester

: 16864-90-7,195502-93-3,195502-94-4
2-(4-chlorophenyl)-3-hydroxypropanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / sodium ethylate / ethanol; dimethylsulfoxide / 0.5 h / Ambient temperature

2: 12.5 percent / aq. NaOH / ethanol / 1) reflux, 5 min, 2) R_.T_., 3 h

With sodium hydroxide; sodium ethanolate; In ethanol; dimethyl sulfoxide;