2-Dimethoxymethyl-3-(4,5-dimethoxy-2-methylphenyl)propanenitrile

Base Information

Chemical Name:2-Dimethoxymethyl-3-(4,5-dimethoxy-2-methylphenyl)propanenitrile
CAS No.:7520-76-5
Molecular Formula:C₁₅H₂₁NO₄
Molecular Weight:279.336
Hs Code.:
Mol file:7520-76-5.mol

Synonyms:2-Dimethoxymethyl-3-(4,5-dimethoxy-2-methylphenyl)propanenitrile

Suppliers and Price of 2-Dimethoxymethyl-3-(4,5-dimethoxy-2-methylphenyl)propanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Dimethoxymethyl-3-(4,5-dimethoxy-2-methylphenyl)propanenitrile

Chemical Property:

Boiling Point:175 - 180 °C (0.03 mmHg)
PSA：60.71000
LogP:2.31338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Dimethoxymethyl-3-(4,5-dimethoxy-2-methylphenyl)propanenitrile

There total 6 articles about 2-Dimethoxymethyl-3-(4,5-dimethoxy-2-methylphenyl)propanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 7520-75-4
4,5-dimethoxy-2-methyl-2'-(methoxymethyl)cinnamonitrile

: 124-41-4
sodium methylate

: 63940-81-8
(Z)-2-(4,5-Dimethoxy-2-methyl-benzyl)-3-methoxy-acrylonitrile

: 7520-76-5
2-Cyan-3-<4,5-Dimethoxy-2-methyl-phenyl>-propionaldehyd-dimethylacetal

Guidance literature:: In methanol; dimethyl sulfoxide; at 85 ℃; for 3.5h;
DOI:10.1021/jo00039a006

Reference yield: 34.0%

: 39800-76-5,1608-82-8
2-(methoxymethylene)-3-methoxypropanenitrile

: 494-99-5
1,2-dimethoxy-4-methylbenzene

: 63940-81-8
(Z)-2-(4,5-Dimethoxy-2-methyl-benzyl)-3-methoxy-acrylonitrile

: 7520-76-5
2-Cyan-3-<4,5-Dimethoxy-2-methyl-phenyl>-propionaldehyd-dimethylacetal

Guidance literature:: With boron trifluoride diethyl etherate; at 60 ℃; for 17h;
DOI:10.1021/jo00039a006

Reference yield:

: 22002-45-5
2-bromo-4-methylanisole

: 7520-76-5
2-Cyan-3-<4,5-Dimethoxy-2-methyl-phenyl>-propionaldehyd-dimethylacetal

Guidance literature:: Multi-step reaction with 2 steps

1: CuCl / dimethylformamide; methanol / 4.5 h / Heating

2: BF₃*OEt₂ / 17 h / 60 °C

With boron trifluoride diethyl etherate; copper(l) chloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jo00039a006