3-(4-Pyridyl)propiolic Acid

Base Information

Chemical Name:3-(4-Pyridyl)propiolic Acid
CAS No.:66869-74-7
Molecular Formula:C₈H₅NO₂
Molecular Weight:147.133
Hs Code.:
European Community (EC) Number:839-284-3

Synonyms:3-(4-Pyridyl)propiolic Acid;66869-74-7;3-pyridin-4-ylprop-2-ynoic acid;MFCD14707287;3-(PYRIDIN-4-YL)PROP-2-YNOIC ACID;3-(4-Pyridyl)propiolicAcid;2-Propynoic acid, 3-(4-pyridinyl)- (9CI);SCHEMBL6121181;AC1699;AKOS012991254;CS-11486;SY022408;FT-0710398;3-(4-Pyridinyl)-2-propynoic acid, AldrichCPR;EN300-122209;A867375

Suppliers and Price of 3-(4-Pyridyl)propiolic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(Pyridin-4-yl)propiolicacid 95+%
5g
$ 855.00

Alichem
3-(Pyridin-4-yl)propiolicacid
25g
$ 4877.60

Alichem
3-(Pyridin-4-yl)propiolicacid
10g
$ 2760.40

Alichem
3-(Pyridin-4-yl)propiolicacid
5g
$ 2010.00

AK Scientific
3-(4-Pyridyl)propiolicacid
1g
$ 458.00

Activate Scientific
3-(4-Pyridyl)propiolic Acid 96+%
5 g
$ 1258.00

Activate Scientific
3-(4-Pyridyl)propiolic Acid 96+%
1 g
$ 422.00

Activate Scientific
3-(4-Pyridyl)propiolic Acid 96+%
250 mg
$ 215.00

Total 8 raw suppliers

Chemical Property of 3-(4-Pyridyl)propiolic Acid

Chemical Property:

PSA：50.19000
LogP:0.51770
Storage Temp.:2-8°C
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:147.032028402
Heavy Atom Count:11
Complexity:205

Purity/Quality:

97% ^*data from raw suppliers

3-(Pyridin-4-yl)propiolicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC=C1C#CC(=O)O

Technology Process of 3-(4-Pyridyl)propiolic Acid

There total 5 articles about 3-(4-Pyridyl)propiolic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 78584-33-5
(pyridyl-4)propiolate de methyle

: 66869-74-7
acide(pyridyl-4)propiolique

Guidance literature:: With potasse methanolique;
DOI:10.1002/jhet.5570180316

Reference yield:

: 55-22-1
pyridine-4-carboxylic acid

: 66869-74-7
acide(pyridyl-4)propiolique

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) d'hexamethyldisilazane; 2.) chlorure de thionyle / 1.) reflux; 2.) temperature ambiante

2: 80 percent

3: 55 percent / termolyse

4: 50 percent / potasse methanolique

With chlorure de thionyle; d'hexamethyldisilazane; potasse methanolique;
DOI:10.1002/jhet.5570180316

Reference yield:

: 14254-57-0
4-(chlorocarbonyl)pyridine

: 66869-74-7
acide(pyridyl-4)propiolique

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent

2: 55 percent / termolyse

3: 50 percent / potasse methanolique

With potasse methanolique;
DOI:10.1002/jhet.5570180316