(pyridyl-4)propiolate de methyle

Base Information

• Chemical Name: (pyridyl-4)propiolate de methyle
• CAS No.: 78584-33-5
• Molecular Formula: C₉H₇NO₂
• Molecular Weight: 161.16
• Hs Code.: 2933399990
• Mol file: 78584-33-5.mol

Synonyms:

Chemical Property of (pyridyl-4)propiolate de methyle

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Methyl 3-(4-pyridyl)propiolate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (pyridyl-4)propiolate de methyle

There total 3 articles about (pyridyl-4)propiolate de methyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

3-Oxo-3-pyridin-4-yl-2-(triphenyl-λ5-phosphanylidene)-propionic acid methyl ester (78584-32-4) → (pyridyl-4)propiolate de methyle (78584-33-5)

Guidance literature:

termolyse;

DOI:10.1002/jhet.5570180316

Reference yield:

pyridine-4-carboxylic acid (55-22-1) → (pyridyl-4)propiolate de methyle (78584-33-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) d'hexamethyldisilazane; 2.) chlorure de thionyle / 1.) reflux; 2.) temperature ambiante

2: 80 percent

3: 55 percent / termolyse

With chlorure de thionyle; d'hexamethyldisilazane;

DOI:10.1002/jhet.5570180316

Reference yield:

4-(chlorocarbonyl)pyridine (14254-57-0) → (pyridyl-4)propiolate de methyle (78584-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent

2: 55 percent / termolyse

DOI:10.1002/jhet.5570180316

upstream raw materials:

3-Oxo-3-pyridin-4-yl-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid methyl ester

pyridine-4-carboxylic acid

4-(chlorocarbonyl)pyridine

Downstream raw materials:

2-(4-pyridyl)ethyne-1-carboxhydrazide

acide(pyridyl-4)propiolique