(6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE

Base Information

• Chemical Name: (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE
• CAS No.: 82763-23-3
• Molecular Formula: C₁₄H₂₁NO
• Molecular Weight: 219.327
• Mol file: 82763-23-3.mol

Synonyms:(6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE;2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-6-METHOXY-N-PROPYL-, HYDROCHLORIDE;6-METHOXY-N-PROPYL-2-AMINOTETRALINE HYDROCHLORIDE

Chemical Property of (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE

Chemical Property:

• PSA: 21.26000
• LogP: 2.94300

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE

There total 1 articles about (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propylamine (107-10-8,42939-71-9) + 6-methoxy-2-tetralone (2472-22-2) → N-propyl-6-methoxy-2-aminotetralin (82763-23-3)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1021/jm00353a016

Reference yield:

N-propyl-6-methoxy-2-aminotetralin (82763-23-3) → N-Propyl-N-[4-(3,4-dimethoxybenzoyloxy)butyl]-6-methoxy-1,2,3,4-tetrahydro-2-naphthylamine (82763-53-9)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / benzene / 2.5 h / Heating

2: LiAlH₄ / benzene / 2.5 h / Heating

3: Et₃N / benzene / 3.5 h / Heating

With lithium aluminium tetrahydride; triethylamine; In benzene;

DOI:10.1021/jm00353a016

upstream raw materials:

propylamine

6-methoxy-2-tetralone

Downstream raw materials:

N-Propyl-N-[4-(3,4-dimethoxybenzoyloxy)butyl]-6-methoxy-1,2,3,4-tetrahydro-2-naphthylamine