α-Hydroxy-4-acetoxybenzenepropionic acid methyl ester

Base Information

Chemical Name:α-Hydroxy-4-acetoxybenzenepropionic acid methyl ester
CAS No.:77573-21-8
Molecular Formula:C12H14O5
Molecular Weight:0
Hs Code.:
Mol file:77573-21-8.mol

Synonyms:3-[4-(Acetyloxy)phenyl]-2-hydroxypropionic acid methyl ester;α-Hydroxy-4-acetoxybenzenepropionic acid methyl ester

Suppliers and Price of α-Hydroxy-4-acetoxybenzenepropionic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of α-Hydroxy-4-acetoxybenzenepropionic acid methyl ester

Chemical Property:

PSA：72.83000
LogP:0.68830

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of α-Hydroxy-4-acetoxybenzenepropionic acid methyl ester

There total 4 articles about α-Hydroxy-4-acetoxybenzenepropionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 864070-64-4
methyl 3-p-acetoxyphenyl-2-t-butyldimethylsiloxy propionate

: 77573-21-8
methyl 3-p-acetoxyphenyl-2-hydroxy propionate

Guidance literature:: With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran;
DOI:10.1016/j.tet.2005.06.022

Reference yield:

: 481072-85-9
methyl 3-p-benzyloxyphenyl-2-t-butyldimethylsiloxy propionate

: 77573-21-8
methyl 3-p-acetoxyphenyl-2-hydroxy propionate

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / hydrogen / Pd/C / ethyl acetate

2: 88 percent / pyridine

3: 98 percent / tetra-n-butylammonium fluoride; acetic acid / tetrahydrofuran

With pyridine; tetrabutyl ammonium fluoride; hydrogen; acetic acid; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;
DOI:10.1016/j.tet.2005.06.022

Reference yield:

: 128316-64-3,481072-37-1
(+/-)-methyl 3-p-benzyloxyphenyl-2-hydroxypropionate

: 77573-21-8
methyl 3-p-acetoxyphenyl-2-hydroxy propionate

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide

2: 87 percent / hydrogen / Pd/C / ethyl acetate

3: 88 percent / pyridine

4: 98 percent / tetra-n-butylammonium fluoride; acetic acid / tetrahydrofuran

With pyridine; 1H-imidazole; dmap; tetrabutyl ammonium fluoride; hydrogen; acetic acid; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2005.06.022