1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid

Base Information

Chemical Name:1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid
CAS No.:336817-91-5
Molecular Formula:C17H22BrNO4
Molecular Weight:384.27
Hs Code.:
DSSTox Substance ID:DTXSID40401512
Mol file:336817-91-5.mol

Synonyms:336817-91-5;1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid;Boc-alpha-(4-bromobenzyl)-DL-Pro-OH;2-[(4-bromophenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic Acid;Boc-|A-(4-bromobenzyl)-DL-Pro-OH;SCHEMBL502217;Boc--(4-brombenzyl)-dl-pro-oh;DTXSID40401512;HY-W142056;Boc- alpha -(4-bromobenzyl)-DL-Pro-OH;CS-0201841;FT-0726503;J-019293;Boc-alpha-(4-bromobenzyl)-DL-Pro-OH, >=96.0% (HPLC);2-(4-Bromobenzyl)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid

Suppliers and Price of 1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Boc-α-(4-bromobenzyl)-DL-Pro-OH ≥96.0% (HPLC)
500mg
$ 270.00

American Custom Chemicals Corporation
BOC-ALPHA-(4-BROMOBENZYL)-DL-PRO-OH 95.00%
1G
$ 669.74

Total 2 raw suppliers

Chemical Property of 1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid

Chemical Property:

Vapor Pressure:2.33E-10mmHg at 25°C
Boiling Point:488.6°C at 760 mmHg
Flash Point:249.3°C
PSA：66.84000
Density:1.412g/cm³
LogP:3.78380
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:383.07322
Heavy Atom Count:23
Complexity:454

Purity/Quality:: Boc-α-(4-bromobenzyl)-DL-Pro-OH ≥96.0% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC1(CC2=CC=C(C=C2)Br)C(=O)O

Technology Process of 1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid

There total 1 articles about 1-Boc-2-(4-bromobenzyl)-2-pyrrolidinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 336818-72-5
N-(tert-butoxycarbonyl)-2-(4-bromobenzyl)proline ethyl ester

: 336817-91-5,706806-77-1,706806-75-9
N-(tert-butoxycarbonyl)-2-(4-bromobenzyl)proline

Guidance literature:: N-(tert-butoxycarbonyl)-2-(4-bromobenzyl)proline ethyl ester; With lithium hydroxide; In tetrahydrofuran; methanol; water; at 20 - 74 ℃;

With sulfuric acid; In water; Acidic aqueous solution;

Reference yield:

: 336817-91-5,706806-77-1,706806-75-9
N-(tert-butoxycarbonyl)-2-(4-bromobenzyl)proline

: C₁₈H₂₃BrNO₄Pol

Guidance literature:: With potassium fluoride; Merrifield resin; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield:

: 336817-91-5,706806-77-1,706806-75-9
N-(tert-butoxycarbonyl)-2-(4-bromobenzyl)proline

: 1021735-89-6
1-amino-4,4-dimethylhexan-2-ol

: 1021734-59-7
tert-butyl 2-(4-bromobenzyl)-2-{[(2-hydroxy-4,4-dimethylhexyl)amino]carbonyl}pyrrolidine-1-carboxylate

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;