5-Bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole

Base Information

Chemical Name:5-Bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole
CAS No.:1020253-11-5
Molecular Formula:C₁₅H₁₃BrN₂O
Molecular Weight:317.185
Hs Code.:2933990090
Mol file:1020253-11-5.mol

Synonyms:Bromides;((4-Bromo-3-methylphenyl)carbonyl)morpholine;(4-Bromo-3-methylphenyl)(morpholino)methanone;(3-Bromobenzoyl)pyrrolidine;(3-Bromophenyl)(pyrrolidin-1-yl)methanone;(4-Bromo-2-fluorophenyl)(4-methoxybenzyl)sulfane;S-(4-Methoxybenzyl) 4-bromo-2-fluorothiophenol;(4-Bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone

Suppliers and Price of 5-Bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 12 raw suppliers

Chemical Property of 5-Bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole

Chemical Property:

Melting Point:45-46°C
PSA：27.05000
LogP:3.85570

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole

There total 3 articles about 5-Bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 4887-88-1
5-bromo-1H-benzo[d]imidazole

: 824-94-2
p-methoxybenzyl chloride

: 1020253-11-5
5-bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole

Guidance literature:: 5-bromo-1H-benzo[d]imidazole; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

p-methoxybenzyl chloride; In tetrahydrofuran; at 60 ℃; for 3h; Temperature;

Reference yield: 60.0%

: 62330-93-2
N'-(2,5-dibromophenyl)-N,N-dimethylformimidamide

: 2393-23-9
4-methoxy-benzylamine

: 1020253-11-5
5-bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole

Guidance literature:: With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; potassium hydroxide; In toluene; at 110 ℃; for 18h; Catalytic behavior; Inert atmosphere;
DOI:10.1080/00397911.2021.1939056

Reference yield:

: 3638-73-1
2,5-dibromoaniline

: 1020253-11-5
5-bromo-1-(4-methoxybenzyl)-1H-benzo[d]imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 6 h / 80 °C

2: potassium hydroxide; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 18 h / 110 °C / Inert atmosphere

With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; potassium hydroxide; In toluene;
DOI:10.1080/00397911.2021.1939056