Methyl 5,5,5-trifluoro-4-(4-fluorophenyliMino)pentaneate

Base Information

• Chemical Name: Methyl 5,5,5-trifluoro-4-(4-fluorophenyliMino)pentaneate
• CAS No.: 936479-70-8
• Molecular Formula: C₁₂H₁₁F₄NO₂
• Molecular Weight: 277.218
• Hs Code.: 2925290090
• Mol file: 936479-70-8.mol

Synonyms:Methyl 5,5,5-trifluoro-4-(4-fluorophenyliMino)pentaneate

Chemical Property of Methyl 5,5,5-trifluoro-4-(4-fluorophenyliMino)pentaneate

Chemical Property:

• PSA: 38.66000
• LogP: 3.41370

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 5,5,5-trifluoro-4-(4-fluorophenyliMino)pentaneate

There total 2 articles about Methyl 5,5,5-trifluoro-4-(4-fluorophenyliMino)pentaneate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 5,5,5-trifluoro-4-oxopentanoate (22581-31-3) + 4-fluoroaniline (371-40-4) → methyl 5,5,5-trifluoro-4-(p-fluorophenylamino)pent-3-enoate + methyl 5,5,5-trifluoro-4-(p-fluorophenylamino)pent-3-enoate (1224599-54-5) + methyl 5,5,5-trifluoro-4-(p-fluorophenylimino)pentanoate (936479-70-8) + methyl 5,5,5-trifluoro-4-(p-fluorophenylimino)pentanoate (1224599-46-5,936479-70-8)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; optical yield given as %de; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.200901424

Reference yield:

methyl 5,5,5-trifluoro-4-oxopentanoate (22581-31-3) + 4-fluoroaniline (371-40-4) → methyl 5,5,5-trifluoro-4-(p-fluorophenylamino)pent-3-enoate + methyl 5,5,5-trifluoro-4-(p-fluorophenylamino)pent-3-enoate (1224599-54-5) + methyl 5,5,5-trifluoro-4-(p-fluorophenylimino)pentanoate (936479-70-8) + methyl 5,5,5-trifluoro-4-(p-fluorophenylimino)pentanoate (1224599-46-5,936479-70-8)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; optical yield given as %de; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.200901424

upstream raw materials:

methyl 5,5,5-trifluoro-4-oxopentanoate

4-fluoroaniline