3-Deoxy-D-arabino-hexonic acid 1,4-lactone

Base Information

• Chemical Name: 3-Deoxy-D-arabino-hexonic acid 1,4-lactone
• CAS No.: 50480-80-3
• Molecular Formula: C6H10O5
• Molecular Weight: 162.142
• Hs Code.: 2932209090
• Mol file: 50480-80-3.mol

Synonyms:3-Deoxy-D-arabino-hexonic acid 1,4-lactone;3-Deoxy-D-arabino-hexonic acid γ-lactone

Chemical Property of 3-Deoxy-D-arabino-hexonic acid 1,4-lactone

Chemical Property:

• PSA: 86.99000
• LogP: -1.98400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Deoxy-D-arabino-hexonic acid 1,4-lactone

There total 9 articles about 3-Deoxy-D-arabino-hexonic acid 1,4-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

4,5,6-trihydroxy-2-oxohexanoic acid (17510-99-5) → 3-deoxy-D-mannonic acid (1518-64-5) + 3-deoxy-D-arabino-hexono-1,4-lactone (499-87-6,6936-66-9,20261-95-4,20261-96-5,50480-80-3,55658-88-3,66537-22-2,79645-44-6,104760-51-2,119008-23-0,134524-29-1)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In water; at 48 ℃; for 9 - 20h; Product distribution / selectivity;

Reference yield:

D-erythro-3-deoxy-[2]hexosulose-bis-phenylhydrazone (32443-72-4) → 3-deoxy-D-arabino-hexono-1,4-lactone (50480-80-3) + 3-deoxy-D-ribo-hexono-1,4-lactone (499-87-6)

Guidance literature:

With 1,4-dioxane; hydrogenchloride;

DOI:10.1039/jr9590003213

Reference yield:

sodium 3-deoxy-D-mannonate (93857-40-0) → D-arabino-3-deoxy-hexonic acid (1518-59-8) + 3-deoxy-D-arabino-hexono-1,4-lactone (50480-80-3)

Guidance literature:

With hydrogenchloride; In water; pH=2 - 6;

upstream raw materials:

D-erythro-3-deoxy-[2]hexosulose-bis-phenylhydrazone

sodium 3-deoxy-D-mannonate

2,3,4,6-tetra-O-acetyl-D-glucono-1,5-lactone

4,5,6-trihydroxy-2-oxohexanoic acid

Downstream raw materials:

3-deoxy-D-ribo-hexono-1,4-lactone

2-Deoxy-D-ribose

3-deoxy-1,2-O-isopropylidene-6-O-tosyl-β-D-arabino-hexofuranose

1,3,6-trideoxy-1,6-imino-D-arabino-hexitol