(4-METHYLPHENYL)ACETONE OXIME

Base Information

• Chemical Name: (4-METHYLPHENYL)ACETONE OXIME
• CAS No.: 114306-23-9
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• Mol file: 114306-23-9.mol

Synonyms:(4-METHYLPHENYL)ACETONE OXIME;2-PROPANONE, 1-(4-METHYLPHENYL)-, OXIME

Chemical Property of (4-METHYLPHENYL)ACETONE OXIME

Chemical Property:

• Melting Point: 90 °C
• Boiling Point: 302.8±21.0 °C(Predicted)
• PKA: 12.18±0.10(Predicted)
• PSA: 32.59000
• Density: 0.98±0.1 g/cm3(Predicted)
• LogP: 2.38760

Purity/Quality:

97% ^*data from raw suppliers

2-PROPANONE, 1-(4-METHYLPHENYL)-, OXIME 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-METHYLPHENYL)ACETONE OXIME

There total 2 articles about (4-METHYLPHENYL)ACETONE OXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1-(4'-methylphenyl)-2-nitropropane (29865-50-7) → 1-(4-methylphenyl)propan-2-one oxime (114306-23-9)

Guidance literature:

With maghemite; methylhydrazine; In ethanol; at 60 ℃; for 12h; chemoselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1002/chem.201504685

Reference yield: 53.0%

p-Tolylaceton (2096-86-8) → 1-(4-methylphenyl)propan-2-one oxime (114306-23-9)

Guidance literature:

With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; for 1h; Reflux;

DOI:10.1021/jo200728t

Reference yield: 70.0%

2,4,6-trinitrochlorobenzene (88-88-0) + 1-(4-methylphenyl)propan-2-one oxime (114306-23-9) → p-Methylbenzylmethylketonoximpikrat (80605-45-4)

Guidance literature:

With pyridine; In acetone; at 0 ℃; for 3h;

upstream raw materials:

p-Tolylaceton

1-(4'-methylphenyl)-2-nitropropane

Downstream raw materials:

4-methylamphetamine

p-Methylbenzylmethylketonoximpikrat

DL-2-Hydroxylamino-1-(4-methyl-phenyl)-propan

3β-(4-chlorophenyl)-2β-[3'-(4-methylbenzyl)isoxazol-5-yl]tropane