2-bromo-5-fluoro-N-(furan-2-ylmethyl)benzamide

Base Information

• Chemical Name: 2-bromo-5-fluoro-N-(furan-2-ylmethyl)benzamide
• CAS No.: 923722-86-5
• Molecular Formula: C₁₂H₉BrFNO₂
• Molecular Weight: 298.111
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID00429292
• Wikidata: Q82242294
• Mol file: 923722-86-5.mol

Synonyms:923722-86-5;2-bromo-5-fluoro-N-(furan-2-ylmethyl)benzamide;N-(Furan-2-ylmethyl) 2-bromo-5-fluorobenzamide;2-Bromo-5-fluoro-N-(fur-2-ylmethyl)benzamide;2-Bromo-5-fluoro-N-[(furan-2-yl)methyl]benzamide;DTXSID00429292;MFCD08872270;AKOS000187981;SB61178;BS-22851;A844212;Z99073303

Chemical Property of 2-bromo-5-fluoro-N-(furan-2-ylmethyl)benzamide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 379.418°C at 760 mmHg
• PKA: 12.65±0.46(Predicted)
• Flash Point: 183.266°C
• PSA: 42.24000
• Density: 1.539g/cm³
• LogP: 3.50210
• Storage Temp.: 2-8°C
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 296.98007
• Heavy Atom Count: 17
• Complexity: 277

Purity/Quality:

98% ^*data from raw suppliers

2-Bromo-5-fluoro-N-(fur-2-ylmethyl)benzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)CNC(=O)C2=C(C=CC(=C2)F)Br

Technology Process of 2-bromo-5-fluoro-N-(furan-2-ylmethyl)benzamide

There total 1 articles about 2-bromo-5-fluoro-N-(furan-2-ylmethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

furan-2-ylmethanamine (617-89-0) + 2-Bromo-5-fluorobenzoic acid (394-28-5) → 2-bromo-5-fluoro-N-(furan-2-ylmethyl)benzamide (923722-86-5)

Guidance literature:

2-Bromo-5-fluorobenzoic acid; With triethylamine; isobutyl chloroformate; In dichloromethane; for 0.25h; Inert atmosphere; Schlenk technique;

furan-2-ylmethanamine; In dichloromethane; at 0 ℃;

DOI:10.1002/ejoc.201501170

upstream raw materials:

furan-2-ylmethanamine

2-Bromo-5-fluorobenzoic acid

Refernces