6-Methoxy-9-[2-O,5-O-bis(1-oxopentyl)-β-D-arabinofuranosyl]-9H-purine

Base Information

Chemical Name:6-Methoxy-9-[2-O,5-O-bis(1-oxopentyl)-β-D-arabinofuranosyl]-9H-purine
CAS No.:137057-69-3
Molecular Formula:C21H30N4O7
Molecular Weight:450.4855
Hs Code.:
Mol file:137057-69-3.mol

Synonyms:6-Methoxy-9-[2-O,5-O-bis(1-oxopentyl)-β-D-arabinofuranosyl]-9H-purine;9-[2-O,5-O-Divaleryl-β-D-arabinofuranosyl]-6-methoxy-9H-purine

Suppliers and Price of 6-Methoxy-9-[2-O,5-O-bis(1-oxopentyl)-β-D-arabinofuranosyl]-9H-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 6-Methoxy-9-[2-O,5-O-bis(1-oxopentyl)-β-D-arabinofuranosyl]-9H-purine

Chemical Property:

PSA：134.89000
LogP:1.92860

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-Methoxy-9-[2-O,5-O-bis(1-oxopentyl)-β-D-arabinofuranosyl]-9H-purine

There total 5 articles about 6-Methoxy-9-[2-O,5-O-bis(1-oxopentyl)-β-D-arabinofuranosyl]-9H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 137057-98-8
Pentanoic acid (2R,3S,4R,5R)-4-(tert-butyl-dimethyl-silanyloxy)-2-(6-methoxy-purin-9-yl)-5-pentanoyloxymethyl-tetrahydro-furan-3-yl ester

: 137057-69-3
Pentanoic acid (2R,3S,4R,5R)-4-hydroxy-2-(6-methoxy-purin-9-yl)-5-pentanoyloxymethyl-tetrahydro-furan-3-yl ester

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h; Yield given; Ambient temperature;
DOI:10.1021/jm00079a006

Reference yield:

: 2082-59-9
pentanoic anhydride

: 137057-69-3
Pentanoic acid (2R,3S,4R,5R)-4-hydroxy-2-(6-methoxy-purin-9-yl)-5-pentanoyloxymethyl-tetrahydro-furan-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 4-(N,N-dimethylamino)pyridine, pyridine / acetonitrile / Ambient temperature

2: aq. Bu₄NF / tetrahydrofuran / 1 h / Ambient temperature

With pyridine; dmap; tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm00079a006

Reference yield:

: 137057-97-7
9-<3-O-(tert-butyldimethylsilyl)-β-D-arabinofuranosyl>-6-methoxy-9H-purine

: 137057-69-3
Pentanoic acid (2R,3S,4R,5R)-4-hydroxy-2-(6-methoxy-purin-9-yl)-5-pentanoyloxymethyl-tetrahydro-furan-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 4-(N,N-dimethylamino)pyridine, pyridine / acetonitrile / Ambient temperature

2: aq. Bu₄NF / tetrahydrofuran / 1 h / Ambient temperature

With pyridine; dmap; tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm00079a006