1-(1H-pyrrolo[3,2-c]pyridin-3-yl)ethanone

Base Information

• Chemical Name: 1-(1H-pyrrolo[3,2-c]pyridin-3-yl)ethanone
• CAS No.: 460053-60-5
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.175
• DSSTox Substance ID: DTXSID00452045
• Nikkaji Number: J1.795.619A
• Wikidata: Q82272400
• Mol file: 460053-60-5.mol

Synonyms:1-(1H-pyrrolo[3,2-c]pyridin-3-yl)ethanone;460053-60-5;3-Acetyl-5-azaindole;Ethanone, 1-(1H-pyrrolo[3,2-c]pyridin-3-yl)- (9CI);SCHEMBL12481581;DTXSID00452045;MFCD11007991;AKOS006304894;AB90172;DS-7179;FT-0653487;1-(1H-Pyrrolo[3,2-c]pyridine-3-yl)ethanone;1-(1H-pyrrolo[3,2-c]pyridin-3-yl)ethan-1-one;A826955

Chemical Property of 1-(1H-pyrrolo[3,2-c]pyridin-3-yl)ethanone

Chemical Property:

• Vapor Pressure: 1.14E-05mmHg at 25°C
• Boiling Point: 370°C at 760 mmHg
• Flash Point: 181.1°C
• PSA: 45.75000
• Density: 1.264g/cm³
• LogP: 1.76550
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 160.063662883
• Heavy Atom Count: 12
• Complexity: 193

Purity/Quality:

97% ^*data from raw suppliers

3-ACETYL-5-AZAINDOLE 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CNC2=C1C=NC=C2

Technology Process of 1-(1H-pyrrolo[3,2-c]pyridin-3-yl)ethanone

There total 1 articles about 1-(1H-pyrrolo[3,2-c]pyridin-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-azaindole (271-34-1) + acetyl chloride (75-36-5) → 3-acetyl-5-azaindole (460053-60-5)

Guidance literature:

With aluminium trichloride; In dichloromethane; at 20 ℃;

DOI:10.1021/jo020135i

upstream raw materials:

5-azaindole

acetyl chloride