6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one

Base Information

Chemical Name:6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one
CAS No.:1156389-00-2
Molecular Formula:C9H7BrFNO
Molecular Weight:244.063
Hs Code.:2933499090
DSSTox Substance ID:DTXSID20656068
Wikidata:Q82570532
Mol file:1156389-00-2.mol

Synonyms:6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one;1156389-00-2;6-bromo-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one;6-bromo-7-fluoro-3,4-dihydro-1H-quinolin-2-one;MFCD12174779;SCHEMBL13732406;DTXSID20656068;QHBQAFBBDSHWLQ-UHFFFAOYSA-N;AKOS009491878;SY016679;CS-0216816;FT-0726619;EN300-61773;Z425366008

Suppliers and Price of 6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one
250mg
$ 330.00

SynQuest Laboratories
6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one
1 g
$ 784.00

Crysdot
6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one 95+%
1g
$ 330.00

Chemenu
6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one 95%
1g
$ 311.00

Apolloscientific
6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one
1g
$ 490.00

American Custom Chemicals Corporation
6-BROMO-7-FLUORO-1,2,3,4-TETRAHYDROQUINOLIN-2-ONE 95.00%
5G
$ 1759.28

Alichem
6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one
5g
$ 1282.05

AK Scientific
6-Bromo-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one
1g
$ 532.00

Total 4 raw suppliers

Chemical Property of 6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one

Chemical Property:

PSA：29.10000
LogP:2.61090
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:242.96950
Heavy Atom Count:13
Complexity:224

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC2=CC(=C(C=C21)Br)F

Technology Process of 6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one

There total 6 articles about 6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 4590-52-7
7-fluoro-3,4-dihydro-1H-quinolin-2-one

: 1156389-00-2
6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 4h;

Reference yield: 88.0%

: 1156389-00-2
6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one

Guidance literature:

Reference yield:

: 372-19-0
meta-fluoroaniline

: 1156389-00-2
6-bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 12 h / 0 - 20 °C

2.1: aluminum (III) chloride / 5 h / 120 °C

2.2: 20 °C / Cooling with ice

3.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 12 h / 0 - 20 °C

With aluminum (III) chloride; N-Bromosuccinimide; triethylamine; In dichloromethane; N,N-dimethyl-formamide;