2-(4-Phenylpiperidin-1-yl)ethanamine

Base Information

Chemical Name:2-(4-Phenylpiperidin-1-yl)ethanamine
CAS No.:41914-43-6
Molecular Formula:C13H20N2
Molecular Weight:204.315
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90423724
Wikidata:Q82235986
Mol file:41914-43-6.mol

Synonyms:2-(4-phenylpiperidin-1-yl)ethanamine;41914-43-6;1-Piperidineethanamine, 4-phenyl-;2-(4-Phenyl-piperidin-1-yl)-ethylamine;4-phenyl-1-Piperidineethanamine;SCHEMBL10360724;DTXSID90423724;BFKSDLKIKGGPJK-UHFFFAOYSA-N;MFCD09055208;AKOS006342708;AB49644;CS-0030291;2-(4-PHENYLPIPERIDIN-1-YL)ETHANAMINE 95%;A1-51502

Suppliers and Price of 2-(4-Phenylpiperidin-1-yl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-phenylpiperidin-1-yl)ethanamine
100mg
$ 130.00

Crysdot
2-(4-Phenylpiperidin-1-yl)ethanamine 95+%
250mg
$ 299.00

ChemBridge Corporation
2-(4-phenylpiperidin-1-yl)ethanamine 95%
1 g
$ 300.00

American Custom Chemicals Corporation
2-(4-PHENYLPIPERIDIN-1-YL)ETHANAMINE 95.00%
5G
$ 1466.85

Total 5 raw suppliers

Chemical Property of 2-(4-Phenylpiperidin-1-yl)ethanamine

Chemical Property:

Vapor Pressure:0.000306mmHg at 25°C
Boiling Point:321°C at 760 mmHg
Flash Point:134.5°C
PSA：29.26000
Density:1.006g/cm³
LogP:2.46290
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:204.162648646
Heavy Atom Count:15
Complexity:167

Purity/Quality:

98%min ^*data from raw suppliers

2-(4-phenylpiperidin-1-yl)ethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1C2=CC=CC=C2)CCN

Technology Process of 2-(4-Phenylpiperidin-1-yl)ethanamine

There total 7 articles about 2-(4-Phenylpiperidin-1-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 2-(2-(4-phenylpiperidin-1-yl)ethyl)isoindoline-1,3-dione

: 41914-43-6
2-(4-phenylpiperidin-1-yl)ethanamine

Guidance literature:: With hydrazine hydrate; In ethanol; at 70 ℃; for 2h;
DOI:10.1016/j.ejmech.2013.12.056

Reference yield:

: 771-99-3
4-phenylpiperidine

: 41914-43-6
2-(4-phenylpiperidin-1-yl)ethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium iodide; sodium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C

2: hydrazine hydrate / ethanol / 2 h / 70 °C

With sodium carbonate; hydrazine hydrate; sodium iodide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2013.12.056

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 41914-43-6
2-(4-phenylpiperidin-1-yl)ethanamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: 2 h / 20 °C

1.3: 15 h / -78 - 20 °C

2.1: palladium on activated charcoal; hydrogen / methanol / 15 h / 20 °C

3.1: trifluoroacetic acid / dichloromethane / 5 h / 0 - 20 °C

4.1: sodium iodide; sodium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C

5.1: hydrazine hydrate / ethanol / 2 h / 70 °C

With n-butyllithium; palladium on activated charcoal; hydrogen; sodium carbonate; hydrazine hydrate; trifluoroacetic acid; sodium iodide; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2013.12.056