2-Phenyl-3-thiophenecarboxylic acid

Base Information

Chemical Name:2-Phenyl-3-thiophenecarboxylic acid
CAS No.:38695-73-7
Molecular Formula:C11H8O2S
Molecular Weight:204.249
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80357241
Wikidata:Q72499028
Mol file:38695-73-7.mol

Synonyms:2-phenylthiophene-3-carboxylic acid;2-phenyl-3-thiophenecarboxylic acid;38695-73-7;SCHEMBL3316024;DTXSID80357241;PQNWWRHSZQZRTB-UHFFFAOYSA-N;2-phenylthiophene-3-carboxylicacid;AKOS015899717;FT-0759651;A851082

Suppliers and Price of 2-Phenyl-3-thiophenecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-PHENYL-3-THIOPHENECARBOXYLIC ACID 95.00%
5MG
$ 501.35

Total 5 raw suppliers

Chemical Property of 2-Phenyl-3-thiophenecarboxylic acid

Chemical Property:

Vapor Pressure:2.96E-05mmHg at 25°C
Boiling Point:342.1°C at 760 mmHg
Flash Point:160.7°C
PSA：65.54000
Density:1.303
LogP:3.11330
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:204.02450067
Heavy Atom Count:14
Complexity:211

Purity/Quality:

97% ^*data from raw suppliers

2-PHENYL-3-THIOPHENECARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C=CS2)C(=O)O

Technology Process of 2-Phenyl-3-thiophenecarboxylic acid

There total 4 articles about 2-Phenyl-3-thiophenecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 38695-70-4
methyl 2-phenylthiophene-3-carboxylate

: 38695-73-7
2-phenylthiophene-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 6h; Reflux;
DOI:10.1016/j.bmc.2014.04.031

Reference yield: 75.8%

: ethyl 2-phenylthiophene-3-carboxylate

: 38695-73-7
2-phenylthiophene-3-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; ethanol; at 15 ℃; for 12h;

Reference yield:

: 98-80-6
phenylboronic acid

: 38695-73-7
2-phenylthiophene-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 5 h / 90 °C

2: sodium hydroxide / ethanol / 6 h / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; sodium hydroxide; In 1,4-dioxane; ethanol; water; 1: |Suzuki-Miyaura Coupling;
DOI:10.1016/j.bmc.2014.04.031